ReviewAntibiotics (Basel, Switzerland)2024
Antimicrobial Metabolites of Caucasian Medicinal Plants as Alternatives to Antibiotics.
Review in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Integrated Botanical and Phytochemical Characterization ofTurkish journal of pharmaceutical sciences · 2026Article
- Biomedical Properties, Developments and Therapeutic Potential of Sesquiterpenoid Lactones and Natural Compounds.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Antimicrobial Peptides and ESKAPEE Pathogens: A New Frontier in the Fight Against Antimicrobial Resistance.Probiotics and antimicrobial proteins · 2026Review
- Antimicrobial Activity of Aurisin A AgainstInternational journal of molecular sciences · 2026Article
- Synergistic antibacterial effects and metabolomic insights inFrontiers in microbiology · 2026Article
- Chitosan Nanoparticles Loaded with Polyphenols for Cosmeceutical Applications: A State-of-the-Art Review.Pharmaceutics · 2025Review
- Antioxidant Potential and Antibacterial Activities of Caucasian Endemic PlantsJournal of xenobiotics · 2025Article
- Antibacterial Activity and Molecular Docking of Lignans Isolated fromPharmaceuticals (Basel, Switzerland) · 2025Article
- Effects of dietary supplementation with Laurus nobilis extract on growth performance, carcass features, blood lipid profile, immunity, antioxidative status, digestive enzymes, and gut microbial load in growing New Zealand white rabbits.Tropical animal health and production · 2025Article
- Neuroprotective Properties of Clove (Biomolecules · 2025Review
- A Review of Botany, Phytochemistry, and Biological Activities of EightMolecules (Basel, Switzerland) · 2025Review
- Antimicrobial Potential of Polyphenols: Mechanisms of Action and Microbial Responses-A Narrative Review.Antioxidants (Basel, Switzerland) · 2025Review
- Traditionally Used Medicinal Plants of Armenia.Plants (Basel, Switzerland) · 2024Review
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- Oxidative Processes and Xenobiotic Metabolism in Plants: Mechanisms of Defense and Potential Therapeutic Implications.Journal of xenobiotics · 2024Review
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- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review explores the potential of antimicrobial metabolites derived from Caucasian medicinal plants as alternatives to conventional antibiotics. With the rise of antibiotic resistance posing a global health threat, there is a pressing need to investigate alternative sources of antimicrobial agents. Caucasian medicinal plants have traditionally been used for their therapeutic properties, and recent research has highlighted their potential as sources of antimicrobial compounds. Representatives of 15 families of Caucasian medicinal plant extracts (24 species) have been explored for their efficacy against these pathogens. The effect of these plants on Gram-positive and Gram-negative bacteria and fungi is discussed in this paper. By harnessing the bioactive metabolites present in these plants, this study aims to contribute to the development of new antimicrobial treatments that can effectively combat bacterial infections while minimizing the risk of resistance emergence. Herein we discuss the following classes of bioactive compounds exhibiting antimicrobial activity: phenolic compounds, flavonoids, tannins, terpenes, saponins, alkaloids, and sulfur-containing compounds of Allium species. The review discusses the pharmacological properties of selected Caucasian medicinal plants, the extraction and characterization of these antimicrobial metabolites, the mechanisms of action of antibacterial and antifungal plant compounds, and their potential applications in clinical settings. Additionally, challenges and future directions in the research of antimicrobial metabolites from Caucasian medicinal plants are addressed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.