Evidence map›Paper›PMID 38927126›Full record

ReviewBiomolecules2024

Silk Sericin and Its Composite Materials with Antibacterial Properties to Enhance Wound Healing: A Review.

Sheng-Lan Wang, Jia-Jun Zhuo, Shou-Min Fang, Wei Xu, Quan-You Yu

Abstract readReview
In one paragraph

Review in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Polysaccharide based biomaterials for advanced wound healing applications.Frontiers in cellular and infection microbiology · 2026
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sheng-Lan WangCollege of Life Science, China West Normal University, Nanchong 637002, China.
Jia-Jun ZhuoSchool of Life Sciences, Chongqing University, Chongqing 400044, China.
Shou-Min FangCollege of Life Science, China West Normal University, Nanchong 637002, China.
Wei XuDepartment of Dermatology, Chongqing Hospital of Traditional Chinese Medicine, No. 40 Daomenkou St., District Yuzhong, Chongqing 400011, China.
Quan-You YuSchool of Life Sciences, Chongqing University, Chongqing 400044, China.ORCID 0000-0002-5747-4595

Funding

National Natural Science Foundation of China U20A2058Natural Science Foundation of Chongqing 2023ZDXM033, cstc2019jcyj-msxmX0741Natural Science Foundation of Sichuan Province 2022NSFSC0069
6 · The paper itself

Abstract

Wound infections may disrupt the normal wound-healing process. Large amounts of antibiotics are frequently used to prevent pathogenic infections; however, this can lead to resistance development. Biomaterials possessing antimicrobial properties have promising applications for reducing antibiotic usage and promoting wound healing. Silk sericin (SS) has been increasingly explored for skin wound healing applications owing to its excellent biocompatibility and antioxidant, antimicrobial, and ultraviolet-resistant properties. In recent years, SS-based composite biomaterials with a broader antimicrobial spectrum have been extensively investigated and demonstrated favorable efficacy in promoting wound healing. This review summarizes various antimicrobial agents, including metal nanoparticles, natural extracts, and antibiotics, that have been incorporated into SS composites for wound healing and elucidates their mechanisms of action. It has been revealed that SS-based biomaterials can achieve sustained antimicrobial activity by slow-release-loaded antimicrobial agents. The antimicrobial-loaded SS composites may promote wound healing through anti-infection, anti-inflammation, hemostasis, angiogenesis, and collagen deposition. The manufacturing methods, benefits, and limitations of antimicrobial-loaded SS materials are briefly discussed. This review aims to enhance the understanding of new advances and directions in SS-based antimicrobial composites and guide future biomedical research.

Indexed as

Anti-Bacterial AgentsBiocompatible MaterialsSericinsWound HealingAnimalsHumansSilkAnti-Bacterial AgentsBiocompatible MaterialsSericinsSilkantibacterialcomposite materialsmechanismsilk sericinwound healing

Identifiers

PMID38927126
PMCPMC11201629

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.