Evidence map›Paper›PMID 38927115›Full record

ArticleBiomolecules2024

De Novo Synthesis of Resveratrol from Sucrose by Metabolically Engineered

Gehad G Ibrahim, Madhavi Perera, Saadiah A Abdulmalek, Jinyong Yan, Yunjun Yan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Introduction of human mMicrobial cell factories · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gehad G IbrahimKey Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.ORCID 0000-0003-2283-3225
Madhavi PereraKey Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Saadiah A AbdulmalekDepartment of Biology, Faculty of Science, Sana'a University, Sana'a 1247, Yemen.ORCID 0000-0002-9185-1104
Jinyong YanKey Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Yunjun YanKey Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.ORCID 0000-0001-6643-597X

Funding

National Natural Science Foundation of China NSFC32170090Wuhan Science and Technology Major Special "Choke Neck" Key Technological Breakthrough Project 2023020302020708
6 · The paper itself

Abstract

Resveratrol, a phenylpropanoid compound, exhibits diverse pharmacological properties, making it a valuable candidate for health and disease management. However, the demand for resveratrol exceeds the capacity of plant extraction methods, necessitating alternative production strategies. Microbial synthesis offers several advantages over plant-based approaches and presents a promising alternative.

Indexed as

Metabolic EngineeringResveratrolSucroseYarrowiaAcyltransferasesAmmonia-LyasesArabidopsisBacterial ProteinsCoenzyme A LigasesFermentationMalonyl Coenzyme ANicotianaRhodotorulaVitis4-coumarate-CoA ligaseAcyltransferasesAmmonia-LyasesBacterial ProteinsCoenzyme A LigasesL-tyrosine ammonia-lyasemalonyl-CoA synthetaseMalonyl Coenzyme AResveratrolstilbene synthaseSucrosemetabolic engineeringmicrobial cell factoryresveratrolYarrowia lipolytica

Identifiers

PMID38927115
PMCPMC11201955

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.