Evidence map›Paper›PMID 38927114›Full record

ArticleBiomolecules2024

Insights into the Effects of Ligand Binding on Leucyl-tRNA Synthetase Inhibitors for Tuberculosis: In Silico Analysis and Isothermal Titration Calorimetry Validation.

Zia Ur Rehman, Asim Najmi, Khalid Zoghebi

Abstract read
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zia Ur RehmanDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia.ORCID 0000-0002-6540-7966
Asim NajmiDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia.ORCID 0000-0002-7529-5523
Khalid ZoghebiDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia.

Funding

Deanship for Research and Innovation, Ministry of Education Saudi Arabia ISP22-16
6 · The paper itself

Abstract

Incidences of drug-resistant tuberculosis have become common and are rising at an alarming rate. Aminoacyl t-RNA synthetase has been validated as a newer target against

Indexed as

Antitubercular AgentsEnzyme InhibitorsLeucine-tRNA LigaseMolecular Docking SimulationMycobacterium tuberculosisCalorimetryComputer SimulationHumansLigandsMolecular Dynamics SimulationProtein BindingTuberculosisAntitubercular AgentsEnzyme InhibitorsLeucine-tRNA LigaseLigandscomputer-aided drug designleucyl t-RNA synthetase inhibitionmolecular dynamics simulationvirtual screening

Identifiers

PMID38927114
PMCPMC11201714

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.