Evidence map›Paper›PMID 38927051›Full record

ArticleBiomolecules2024

Neuroprotective Strategies and Cell-Based Biomarkers for Manganese-Induced Toxicity in Human Neuroblastoma (SH-SY5Y) Cells.

Catherine M Cahill, Sanjan S Sarang, Rachit Bakshi, Ning Xia, Debomoy K Lahiri, Jack T Rogers

Abstract read
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Catherine M CahillNeurochemistry Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.
Sanjan S SarangNeurochemistry Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.
Rachit BakshiNeurochemistry Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.
Ning XiaNeurochemistry Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.
Debomoy K LahiriDepartment of Psychiatry and Medical & Molecular Genetics, Indiana Alzheimer's Disease Research Center, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.ORCID 0000-0002-1664-5933
Jack T RogersNeurochemistry Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.

Funding

TAU, AB, SYNUCLEIN AND NITRATIVE/OXIDATIVE DAMAGE IN MCIP01AG014449 · NIA · UNIVERSITY OF PITTSBURGH · PI IKONOMOVIC, MILOS D · 1997 to 2024
$39.7M
Research Education ComponentP30AG072976 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI ANDREW J SAYKIN · 2021 to 2026
$24.1M
Role of microRNA in regulating Fe, Amyloid, and Tau (FeAT) in Alzheimer's diseaseR56AG072810 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI LAHIRI, DEBOMOY K · 2021 to 2021
$630k
Brain protein alteration by vascular overexpressed miRNA (BravomiR)R21AG076202 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI LAHIRI, DEBOMOY K · 2022 to 2022
$435k
Michael J. Fox Foundation for Parkinson's Research 007382NIA NIH HHS P01 AG014449NIA NIH HHS P30 AG072976NIA NIH HHS R21 AG076202NIA NIH HHS R56 AG072810
6 · The paper itself

Abstract

Manganese (Mn) is an essential heavy metal in the human body, while excess

Indexed as

ManganeseNeuroblastomaBiomarkersCell Line, TumorCell SurvivalHumansNeuroprotective AgentsBiomarkersManganeseNeuroprotective Agentsamyloid precursor protein (APP)ferritininflammationmanganese neurotoxicitymetallothionein-IIImRNAsneuroprotectionoxidative stressParkinsonismuntranslated regionsurate

Identifiers

PMID38927051
PMCPMC11201412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.