Evidence map›Paper›PMID 38926721›Full record

ArticleJournal of nanobiotechnology2024

Self-assembled copper-based nanoparticles for enzyme catalysis-enhanced chemodynamic/photodynamic/antiangiogenic tritherapy against hepatocellular carcinoma.

Yaping Wang, Xun Zhang, Yunfeng Ma, Xiaobo Zhou, Weijun Xu, Sida Qin, Chengcheng Yang

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Targeting cuproptosis in liver cancer: Molecular mechanisms and therapeutic implications.Apoptosis : an international journal on programmed cell death · 2025
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yaping WangDepartment of Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Xun ZhangDepartment of Thoracic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Yunfeng MaDepartment of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, 710061, China.
Xiaobo ZhouDepartment of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, 710061, China.
Weijun XuState Key Laboratory for Mechanical Behavior of Materials, Xi'an Jiaotong University, Xi'an, 710049, China. weijun.xu@mail.xjtu.edu.cn.
Sida QinDepartment of Thoracic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China. qinsida@xjtu.edu.cn.
Chengcheng YangDepartment of Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China. ccyang@xjtufh.edu.cn.

Funding

China Postdoctoral Science Foundation 2023M732800Medical basic-clinical Integration and innovation Foundation of Xi'an Jiaotong University YXJLRH2022001National Natural Science Foundation of China 52103185
6 · The paper itself

Abstract

As an emerging cancer treatment strategy, reactive oxygen species-based tumor catalytic therapies face enormous challenges due to hypoxia and the overexpression of glutathione (GSH) in the tumor microenvironment. Herein, a self-assembled copper-based nanoplatform, TCCHA, was designed for enzyme-like catalysis-enhanced chemodynamic/photodynamic/antiangiogenic tritherapy against hepatocellular carcinoma. TCCHA was fabricated from Cu

Indexed as

Carcinoma, HepatocellularCopperLiver NeoplasmsPhotochemotherapyPhotosensitizing AgentsAngiogenesis InhibitorsAnimalsAntineoplastic AgentsCatalysisCell Line, TumorChlorophyllidesDrug LiberationGlutathioneHumansMetal NanoparticlesMiceAngiogenesis InhibitorsAntineoplastic AgentsChlorophyllidesCopperGlutathionePhotosensitizing AgentsphytochlorinPorphyrinsReactive Oxygen SpeciesAntiangiogenesisCoordination self-assemblyCopper nanozymeReactive oxygen speciesSynergistic therapy

Identifiers

PMID38926721
PMCPMC11202248

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.