Evidence map›Paper›PMID 38926717›Full record

ArticleBMC musculoskeletal disorders2024

Clinical and imaging findings associated with preservation of knee joint health over 8 years in individuals aged 65 and over: data from the OAI.

Felix G Gassert, Gabby B Joseph, John A Lynch, Johanna Luitjens, Michael C Nevitt, Charles E McCulloch, Nancy E Lane, Sharmila Majumdar, Thomas M Link

Abstract read
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In one paragraph

Article in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Felix G GassertDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 185 Berry Street, Lobby 6, Suite 350, San Francisco, CA, 94107, USA. felix.gassert@tum.de.
Gabby B JosephDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 185 Berry Street, Lobby 6, Suite 350, San Francisco, CA, 94107, USA.
John A LynchDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 185 Berry Street, Lobby 6, Suite 350, San Francisco, CA, 94107, USA.
Johanna LuitjensDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 185 Berry Street, Lobby 6, Suite 350, San Francisco, CA, 94107, USA.
Michael C NevittDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Charles E McCullochDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Nancy E LaneCenter for Musculoskeletal Health, Department of Medicine, University of California, Davis, CA, USA.
Sharmila MajumdarDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 185 Berry Street, Lobby 6, Suite 350, San Francisco, CA, 94107, USA.
Thomas M LinkDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 185 Berry Street, Lobby 6, Suite 350, San Francisco, CA, 94107, USA.

Funding

Understanding the mechanisms by which weight change affects progression of knee osteoarthritis in obese and overweight individuals: An analysis of the Osteoarthritis Initiative DatasetR01AR078917 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GABRIELLE JOSEPH, THOMAS M LINK · 2021 to 2026
$3.4M
NIAMS NIH HHS R01 AR078917NIH HHS NIH R01-AR064771, NIH R01-AR078917, R01-AG070647, N01-AR-2-2258; N01-AR-2-2259; N01-AR-2-2260; N01-AR-2-2261; N01-AR-2-2262
6 · The paper itself

Abstract

objectiveWhile risk factors for osteoarthritis (OA) are well known, it is not well understood why certain individuals maintain high mobility and joint health throughout their life while others demonstrate OA at older ages. The purpose of this study was to assess which demographic, clinical and MRI quantitative and semi-quantitative factors are associated with preserving healthy knees in older individuals.

methodsThis study analyzed data from the OA Initiative (OAI) cohort of individuals at the age of 65 years or above. Participants without OA at baseline (BL) (Kellgren-Lawrence (KL) ≤ 1) were followed and classified as incident cases (KL ≥ 2 during follow-up; n = 115) and as non-incident (KL ≤ 1 over 96-month; n = 391). Associations between the predictor-variables sex, age, BMI, race, clinical scoring systems, T

resultsObesity and presence of pain showed a significant inverse association with maintaining radiographically normal joints in patients aged 65 and above. T

conclusionOverall, this study provides protective clinical parameters as well as quantitative and semi-quantitative MR-imaging parameters associated with maintaining radiographically normal knee joints in an older population over 8 years.

Indexed as

Knee JointMagnetic Resonance ImagingOsteoarthritis, KneeAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleObesityRisk FactorsMagnetic resonance imagingOlder individualsOsteoarthritisProtective factors

Identifiers

PMID38926717
PMCPMC11201086

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.