Evidence map›Paper›PMID 38926670›Full record

ReviewThe Journal of organic chemistry2024

Metal-Hydride C-C Cross-Coupling of Alkenes Through a Double Outer-Sphere Mechanism.

Nathan Dao, Xu-Cheng Gan, Ryan A Shenvi

Abstract readReview
In one paragraph

Review in The Journal of organic chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Discovery of a phenazine-thiol conjugase from sparse data using genome-informed machine learning.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Boron-Mediated Hydroalkylation of Unactivated Olefins: AnJournal of the American Chemical Society · 2026
    Article
  3. Article
  4. Review
  5. Radical Sorting Catalysis via Bimolecular Homolytic Substitution (SJournal of the American Chemical Society · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nathan DaoDepartment of Chemistry, Scripps Research, La Jolla, California 92037, United States.
Xu-Cheng GanDepartment of Chemistry, Scripps Research, La Jolla, California 92037, United States.ORCID 0000-0001-7404-3087
Ryan A ShenviDepartment of Chemistry, Scripps Research, La Jolla, California 92037, United States.ORCID 0000-0001-8353-6449

Funding

Unusual Pharmacophores and New Tools for Cross-CouplingR35GM122606 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI Ryan Ashok Shenvi · 2017 to 2026
$7.1M
NIGMS NIH HHS R35 GM122606
6 · The paper itself

Abstract

This Synopsis covers recent reports of metal-catalyzed alkene functionalizations that likely involve iterative outer-sphere reactions in which the substrate reacts directly with a metal ligand instead of with the metal center itself. Traditional metal hydride-catalyzed alkene functionalizations involve this latter pathway whereby the alkene forms part of the metal ligand sphere (i.e. an inner-sphere reaction). In contrast, alkenes do not ligate the metal in so-called outer-sphere reactions and instead react with a metal ligand. These transformations have proved crucial for the synthesis of high fraction sp

Identifiers

PMID38926670
PMCPMC11827411

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.