Evidence map›Paper›PMID 38926614›Full record

ArticleNature2024

Molecular basis for transposase activation by a dedicated AAA+ ATPase.

Álvaro de la Gándara, Mercedes Spínola-Amilibia, Lidia Araújo-Bazán, Rafael Núñez-Ramírez, James M Berger, Ernesto Arias-Palomo

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Álvaro de la Gándara *Centro de Investigaciones Biológicas Margarita Salas, CSIC, Madrid, Spain.
Mercedes Spínola-Amilibia *Centro de Investigaciones Biológicas Margarita Salas, CSIC, Madrid, Spain.ORCID 0000-0002-0641-8809
Lidia Araújo-BazánCentro de Investigaciones Biológicas Margarita Salas, CSIC, Madrid, Spain.ORCID 0000-0002-8750-7706
Rafael Núñez-RamírezCentro de Investigaciones Biológicas Margarita Salas, CSIC, Madrid, Spain.
James M BergerDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA. jmberger@jhmi.edu.ORCID 0000-0003-0666-1240
Ernesto Arias-PalomoCentro de Investigaciones Biológicas Margarita Salas, CSIC, Madrid, Spain. earias@cib.csic.es.ORCID 0000-0002-2706-7411

Funding

Mechanistic Studies of Replication Initiation in ProkaryotesR37GM071747 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI James M. Berger · 2017 to 2026
$4.4M
Structure/Function Studies of DNA Replication InitiationR01GM071747 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BERGER, JAMES M. · 2005 to 2016
$4.0M
NIGMS NIH HHS R01 GM071747NIGMS NIH HHS R37 GM071747Wellcome Trust
6 · The paper itself

Abstract

Transposases drive chromosomal rearrangements and the dissemination of drug-resistance genes and toxins

Indexed as

AAA DomainAdenosine TriphosphatasesTransposasesCatalytic DomainCryoelectron MicroscopyDNADNA Transposable ElementsEnzyme ActivationModels, MolecularProtein MultimerizationAdenosine TriphosphatasesDNADNA Transposable ElementsTransposases

Identifiers

PMID38926614
PMCPMC11208146

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.