Evidence map›Paper›PMID 38926576›Full record

ArticleNature2024

Oxylipins and metabolites from pyroptotic cells act as promoters of tissue repair.

Parul Mehrotra, Sophia Maschalidi, Laura Boeckaerts, Christian Maueröder, Rochelle Tixeira, Jonathan Pinney, Javier Burgoa Cardás, Vladimir Sukhov, Yunus Incik, Christopher J Anderson and 10 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed.

  1. The gasdermin family: from pyroptosis mechanisms to therapeutic targets.Signal transduction and targeted therapy · 2026
    Review
  2. Pyroptotic cell-derived factors promote osteoclast differentiation.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
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  15. Review
  16. Fibrous-layer resident Angptl7Cell research · 2026
    Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Parul Mehrotra *VIB-UGent Center for Inflammation Research, Ghent, Belgium. pmehrotra@iitd.ac.in.
Sophia Maschalidi *VIB-UGent Center for Inflammation Research, Ghent, Belgium.
Laura BoeckaertsVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Christian MaueröderVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Rochelle TixeiraVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Jonathan PinneyUniversity of Virginia, Charlottesville, VA, USA.
Javier Burgoa CardásVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Vladimir SukhovITMO University, St Petersburg, Russia.
Yunus IncikVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Christopher J AndersonVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Bing HuVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Burcu N KeçeliVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Amanda GoncalvesVIB Bio Imaging Core, Ghent, Belgium.
Lieselotte Vande WalleDepartment of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
Nina Van OpdenboschDepartment of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
Alexey SergushichevITMO University, St Petersburg, Russia.ORCID 0000-0003-1159-7220
Esther HosteVIB-UGent Center for Inflammation Research, Ghent, Belgium.ORCID 0000-0002-3181-431X
Umang JainDivision of Anatomic and Molecular Pathology, Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Mohamed LamkanfiDepartment of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.ORCID 0000-0002-4898-7663
Kodi S RavichandranVIB-UGent Center for Inflammation Research, Ghent, Belgium. kodi@wustl.edu.ORCID 0000-0001-9049-1410

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyroptosis is a lytic cell death mode that helps limit the spread of infections and is also linked to pathology in sterile inflammatory diseases and autoimmune diseases

Indexed as

MacrophagesOxylipinsPyroptosisSecretomeWound HealingAnimalsCaspase 1Cell MovementCell ProliferationCyclooxygenase 2DinoprostoneFemaleFibroblastsGasderminsHumansInflammasomesCaspase 1Cyclooxygenase 2DinoprostoneGasderminsInflammasomesInterleukin-1betaOxylipinsPhosphate-Binding Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.