Evidence map›Paper›PMID 38926468›Full record

ArticleScientific reports2024

Optimized spray-dried conditions' impact on fatty acid profiles and estimation of in vitro digestion of spray-dried chia/fish oil microcapsules.

Muhammad Abdul Rahim, Joe M Regenstein, Fahad Al-Asmari, Muhammad Imran, Mohamed Fawzy Ramadan, João Miguel F Rocha, Imtiaz Hussain, Eliasse Zongo

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Muhammad Abdul RahimDepartment of Food Science and Nutrition, Faculty of Medicine and Allied Health Sciences, Times Institute, Multan, Pakistan. mabdulrahim@t.edu.pk.
Joe M RegensteinDepartment of Food Science, Cornell University, Ithaca, NY, USA.
Fahad Al-AsmariDepartment of Food and Nutrition Sciences, College of Agricultural and Food Sciences, King Faisal University, 31982, Hofuf, Al-Ahsa, Kingdom of Saudi Arabia.
Muhammad ImranDepartment of Food Science, Faculty of Life Sciences, Government College University, Faisalabad, 38000, Pakistan.
Mohamed Fawzy RamadanDepartment of Clinical Nutrition, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia.
João Miguel F RochaCBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005, Porto, Portugal.
Imtiaz HussainDepartment of Food Science and Technology, Faculty of Agriculture, University of Poonch, Rawalakot, Azad Kashmir, Pakistan.
Eliasse ZongoLaboratoire de Recherche et d'Enseignement en Santé et Biotechnologies Animales, Université Nazi BONI, 01 BP 1091, Bobo Dioulasso, Burkina Faso. zongoeliasse@yahoo.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-chain polyunsaturated fatty acids (LCPUFA) are of interest due to their potential health properties and have a significant role in reducing the risk of various chronic diseases in humans. It is commonly used as a supplement. However, lipid oxidation is an important negative factor caused by environmental, processing, and limited water solubility of LCPUFA, making them difficult to incorporate into food products. The objective of this research work was to prevent oxidation, extend shelf life, enhance the stability of fatty acids, and to achieve controlled release by preparing spray-dried powder (SDM). For spray-drying, aqueous emulsion blends were formulated using a 1:1 ratio of chia seed oil (CSO) and fish oil (FO) and using a laboratory-scale spray-dryer with varying conditions: inlet air temperature (IAT, 125-185 °C), wall material (WM, 5-25%), pump speed (PS, 3-7 mL/min), and needle speed (NS, 3-11 s). The maximum alpha-linolenic acid (ALA) content was 33 ± 1%. The highest values of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in the microcapsules were 8.4 ± 0.4 and 13 ± 1%, respectively. Fourier transform infrared and X-Ray diffraction analysis results indicated that SDM was successfully formulated with Gum Arabic and maltodextrin (MD). The blending without encapsulation of CSO and FO was digested more efficiently and resulted in more oil being released with simulated gastric fluid (SGF), simulated intestinal fluid (SIF), and SGF + SIF conditions without heating. No significant changes were observed for saturated, monounsaturated, and LCPUFA, whether exposed or not to gastrointestinal conditions. However, compared to the release of SDM, it can be useful for designing delivery systems for the controlled release of essential fatty acids.

Indexed as

CapsulesFish OilsSpray DryingFatty AcidsHumansPlant OilsSalviaCapsulesFatty AcidsFish OilsPlant OilsChia seedsControlled releaseFish oilLong–chain polyunsaturated fatty acidsSpray–drying

Identifiers

PMID38926468
PMCPMC11208571

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.