Evidence map›Paper›PMID 38926427›Full record

Trial reportScientific reports2024

Clinical evaluation of AI-assisted muscle ultrasound for monitoring muscle wasting in ICU patients.

Phung Tran Huy Nhat, Nguyen Van Hao, Lam Minh Yen, Nguyen Hoang Anh, Dong Phu Khiem, Hamideh Kerdegari, Le Thanh Phuong, Vo Tan Hoang, Nguyen Thanh Ngoc, Le Ngoc Minh Thu and 10 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Undetected Weight Loss Associates With Upstaging in Cancer Patients.Journal of cachexia, sarcopenia and muscle · 2026
    Article
  3. Article
  4. Article
  5. Observational
  6. Application of Artificial Intelligence in Physical Rehabilitation of Patients Admitted to the Intensive Care Unit: A Scoping Review.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Phung Tran Huy NhatSchool of Biomedical Engineering Imaging Sciences, King's College London, London, UK. nhat.phung@kcl.ac.uk.
Nguyen Van HaoHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Lam Minh YenOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Nguyen Hoang AnhHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Dong Phu KhiemNational Hospital for Tropical Diseases, Hanoi, Vietnam.
Hamideh KerdegariSchool of Biomedical Engineering Imaging Sciences, King's College London, London, UK.
Le Thanh PhuongOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Vo Tan HoangOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Nguyen Thanh NgocOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Le Ngoc Minh ThuHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Truong Ngoc TrungHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Luigi PisaniMahidol Oxford Research Unit, Bangkok, Thailand.
VITAL Consortium
Reza RazaviSchool of Biomedical Engineering Imaging Sciences, King's College London, London, UK.
Sophie YacoubOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Nguyen Van Vinh ChauHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Andrew P KingSchool of Biomedical Engineering Imaging Sciences, King's College London, London, UK.
Louise ThwaitesOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Linda DenehyUniversity of Melbourne, Melbourne, Australia.
Alberto GomezSchool of Biomedical Engineering Imaging Sciences, King's College London, London, UK.

Funding

Wellcome TrustWellcome Trust 217650/Z/19/Z
6 · The paper itself

Abstract

Muscle ultrasound has been shown to be a valid and safe imaging modality to assess muscle wasting in critically ill patients in the intensive care unit (ICU). This typically involves manual delineation to measure the rectus femoris cross-sectional area (RFCSA), which is a subjective, time-consuming, and laborious task that requires significant expertise. We aimed to develop and evaluate an AI tool that performs automated recognition and measurement of RFCSA to support non-expert operators in measurement of the RFCSA using muscle ultrasound. Twenty patients were recruited between Feb 2023 and July 2023 and were randomized sequentially to operators using AI (n = 10) or non-AI (n = 10). Muscle loss during ICU stay was similar for both methods: 26 ± 15% for AI and 23 ± 11% for the non-AI, respectively (p = 0.13). In total 59 ultrasound examinations were carried out (30 without AI and 29 with AI). When assisted by our AI tool, the operators showed less variability between measurements with higher intraclass correlation coefficients (ICCs 0.999 95% CI 0.998-0.999 vs. 0.982 95% CI 0.962-0.993) and lower Bland Altman limits of agreement (± 1.9% vs. ± 6.6%) compared to not using the AI tool. The time spent on scans reduced significantly from a median of 19.6 min (IQR 16.9-21.7) to 9.4 min (IQR 7.2-11.7) compared to when using the AI tool (p < 0.001). AI-assisted muscle ultrasound removes the need for manual tracing, increases reproducibility and saves time. This system may aid monitoring muscle size in ICU patients assisting rehabilitation programmes.

Indexed as

Critical IllnessIntensive Care UnitsMuscular AtrophyUltrasonographyAdultAgedArtificial IntelligenceFemaleHumansMaleMiddle AgedMuscle, SkeletalQuadriceps MuscleArtificial intelligenceIntensive care unitMuscle ultrasoundMuscle wastingReal-time

Identifiers

PMID38926427
PMCPMC11208490

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.