Evidence map›Paper›PMID 38926424›Full record

ArticleNature communications2024

Fructooligosaccharides benefits on glucose homeostasis upon high-fat diet feeding require type 2 conventional dendritic cells.

Adélaïde Gélineau, Geneviève Marcelin, Melissa Ouhachi, Sébastien Dussaud, Lise Voland, Raoul Manuel, Ines Baba, Christine Rouault, Laurent Yvan-Charvet, Karine Clément and 3 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Combined pharmacological targeting of CD9Cell reports. Medicine · 2025
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Adélaïde GélineauSorbonne Université, Institut National de la Santé et de la Recherche Médicale, Inserm, Research Unit on Cardiovascular and Metabolic Diseases, Hôpital de la Pitié-Salpêtrière, Paris, France.ORCID 0000-0002-5140-7981
Geneviève MarcelinSorbonne Université, Institut National de la Santé et de la Recherche Médicale, Inserm, Nutrition and Obesities: Systemic approaches research group, NutriOmics, Paris, France.
Melissa OuhachiSorbonne Université, Institut National de la Santé et de la Recherche Médicale, Inserm, Research Unit on Cardiovascular and Metabolic Diseases, Hôpital de la Pitié-Salpêtrière, Paris, France.
Sébastien DussaudSorbonne Université, Institut National de la Santé et de la Recherche Médicale, Inserm, Research Unit on Cardiovascular and Metabolic Diseases, Hôpital de la Pitié-Salpêtrière, Paris, France.ORCID 0000-0002-5365-8338
Lise VolandSorbonne Université, Institut National de la Santé et de la Recherche Médicale, Inserm, Nutrition and Obesities: Systemic approaches research group, NutriOmics, Paris, France.
Raoul ManuelSorbonne Université, Institut National de la Santé et de la Recherche Médicale, Inserm, Research Unit on Cardiovascular and Metabolic Diseases, Hôpital de la Pitié-Salpêtrière, Paris, France.
Ines BabaSorbonne Université, Institut National de la Santé et de la Recherche Médicale, Inserm, Research Unit on Cardiovascular and Metabolic Diseases, Hôpital de la Pitié-Salpêtrière, Paris, France.
Christine RouaultSorbonne Université, Institut National de la Santé et de la Recherche Médicale, Inserm, Nutrition and Obesities: Systemic approaches research group, NutriOmics, Paris, France.
Laurent Yvan-CharvetInstitut National de la Santé et de la Recherche Médicale, Inserm, Université Côte d'Azur, Centre Méditerranéen de Médecine Moléculaire (C3M), Atip-Avenir, Fédération Hospitalo-Universitaire (FHU) Oncoage, Nice, France.ORCID 0000-0002-7748-4942
Karine ClémentSorbonne Université, Institut National de la Santé et de la Recherche Médicale, Inserm, Nutrition and Obesities: Systemic approaches research group, NutriOmics, Paris, France.ORCID 0000-0002-2489-3355
Roxane TussiwandNational Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-1712-868X
Thierry HubySorbonne Université, Institut National de la Santé et de la Recherche Médicale, Inserm, Research Unit on Cardiovascular and Metabolic Diseases, Hôpital de la Pitié-Salpêtrière, Paris, France.
Emmanuel L GautierSorbonne Université, Institut National de la Santé et de la Recherche Médicale, Inserm, Research Unit on Cardiovascular and Metabolic Diseases, Hôpital de la Pitié-Salpêtrière, Paris, France. emmanuel-laurent.gautier@inserm.fr.ORCID 0000-0003-2976-7566

Funding

Dendritic cells heterogeneity and functionZIADE000752 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI TUSSIWAND, ROXANE · 2019 to 2025
$10.5M
Agence Nationale de la Recherche (French National Research Agency) ANR-17-CE14-0009Agence Nationale de la Recherche (French National Research Agency) ANR-17-CE14-0023Agence Nationale de la Recherche (French National Research Agency) ANR-21-CE14-0023Fondation de France 00056835
6 · The paper itself

Abstract

Diet composition impacts metabolic health and is now recognized to shape the immune system, especially in the intestinal tract. Nutritional imbalance and increased caloric intake are induced by high-fat diet (HFD) in which lipids are enriched at the expense of dietary fibers. Such nutritional challenge alters glucose homeostasis as well as intestinal immunity. Here, we observed that short-term HFD induced dysbiosis, glucose intolerance and decreased intestinal RORγt

Indexed as

Dendritic CellsDiet, High-FatHomeostasisMice, Inbred C57BLOligosaccharidesAnimalsDietary FiberDysbiosisGastrointestinal MicrobiomeGlucoseGlucose IntoleranceInterleukin-17MaleMiceNuclear Receptor Subfamily 1, Group F, Member 3Th17 CellsDietary FiberfructooligosaccharideGlucoseInterleukin-17Nuclear Receptor Subfamily 1, Group F, Member 3Oligosaccharides

Identifiers

PMID38926424
PMCPMC11208547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.