Evidence map›Paper›PMID 38926371›Full record

Trial reportZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2024

[Efficacy and safety of dust mite subcutaneous immunotherapy in children with allergic asthma: a prospective randomized controlled study].

Ya-Ni Wang, Si-Qi Lu, Hai Chen, Yu-Qin Li, Hong-Yan Lu, Hui Zhu, Ming Chang

Abstract readRandomized Controlled TrialEnglish Abstract
In one paragraph

Trial report in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ya-Ni WangDepartment of Pediatrics, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China.
Si-Qi LuDepartment of Pediatrics, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China.
Hai ChenDepartment of Pediatrics, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China.
Yu-Qin LiDepartment of Pediatrics, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China.
Hong-Yan LuDepartment of Pediatrics, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China.
Hui ZhuDepartment of Pediatrics, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China.
Ming ChangDepartment of Pediatrics, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the efficacy and safety of subcutaneous immunotherapy (SCIT) using dust mites in children with allergic asthma.

methodsIn a prospective randomized controlled study, 98 children with dust mite-induced allergic asthma were randomly divided into a control group (

resultsCompared with pre-treatment levels, the SCIT group showed a significant reduction in the percentage of peripheral blood eosinophils, VAS, total medication score, and FeNO, while lung function significantly improved, and asthma control levels were better 3 years after treatment (

conclusionsSCIT is an effective and safe treatment for allergic asthma in children.

Indexed as

AsthmaPyroglyphidaeAdolescentAnimalsChildChild, PreschoolDesensitization, ImmunologicFemaleHumansInjections, SubcutaneousMaleProspective StudiesAllergic asthmaChildEfficacySafetySubcutaneous immunotherapy

Identifiers

PMID38926371
PMCPMC11562054

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.