ArticleArchives of gynecology and obstetrics2024
Clinical characteristics and perinatal outcome of fetuses with ventriculomegaly.
Article in Archives of gynecology and obstetrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Congenital Anomaly Prevalence: A 10-Year Retrospective Study in a Tertiary Hospital in Turkey.Birth defects research · 2026Article
- Pregnancy and early neurodevelopment after prenatal ventriculomegaly: a 2011-2024 single-center retrospective cohort of 983 cases.BMC pregnancy and childbirth · 2026Article
- Clinical characteristics and outcome of fetuses with ventriculomegaly: a retrospective multicenter study.Archives of gynecology and obstetrics · 2026Article
- Antenatally Diagnosed Ventriculomegaly: Postnatal Clinical Course and Neurodevelopmental Insights.Yonsei medical journal · 2025Article
- Management of Prenatally Diagnosed Malformations of the Central Nervous System: Factors Influencing Decision-making and the Time of Termination of Pregnancy.Geburtshilfe und Frauenheilkunde · 2025Article
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Authors and funding
7 authors.
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Abstract
purposeTo assess the incidence of associated structural anomalies, chromosomal/genetic abnormalities, infections, and perinatal outcomes of fetuses with ventriculomegaly (VM), also to evaluate the role of fetal magnetic resonance imaging (MRI) in detecting associated intracranial anomalies.
methodsRetrospective cohort study of 149 prenatally diagnosed pregnancies with fetal VM. VM was classified as mild (Vp = 10-12 mm), moderate (Vp = 12.1-15 mm), and severe (Vp > 15 mm). Fetal MRI was performed to 97 pregnancies.
resultsThe incidences of an associated CNS, non-CNS, chromosomal anomaly, genetic abnormality and fetal infection were 42.3%, 11.4%, 6.1%, 2.1% and 1.3%, respectively. Fetal MRI identified additional CNS anomalies in 6.7% of cases, particularly in severe VM. The incidences of perinatal outcomes were 18.8% termination of pregnancy, 4% intrauterine and 8.1% neonatal or infant death. The rates of fetuses alive at > 12 months of age with neurological morbidity were 2.6%, 11.1% and 76.9% for mild, moderate and severe isolated VM, respectively.
conclusionThe prognosis of fetuses with VM mostly depends on the severity and the associated anomalies. Mild to moderate isolated VM generally have favorable outcomes. Fetal MRI is particularly valuable in fetuses with isolated severe VM.
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