Evidence map›Paper›PMID 38926183›Full record

ReviewNeuroradiology2024

Isolated cerebellar stroke in a paediatric patient with typical haemolytic uraemic syndrome: a case report and literature review.

Manuela Lo Bianco, Sergio Rinella, Felice D'Arco, Evangelia Ioannidou, Marios Kaliakatsos

Abstract readCase ReportsReview
In one paragraph

Review in Neuroradiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Manuela Lo BiancoPostgraduate Training Program in Pediatrics, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.ORCID http://orcid.org/0000-0002-5413-419X
Sergio RinellaDepartment of Educational Sciences, University of Catania, Catania, Italy. sergio.rinella@hotmail.com.ORCID http://orcid.org/0000-0002-9368-7088
Felice D'ArcoDepartment of Neuroradiology, Great Ormond Street Hospital for Children, London, UK.ORCID http://orcid.org/0000-0001-7396-591X
Evangelia IoannidouPaediatric Specialty Trainee in Paediatric Neurology, Great Ormond Street Hospital for Children, London, UK.ORCID http://orcid.org/0000-0003-0422-1727
Marios KaliakatsosDepartment of Neurology, Great Ormond Street Hospital for Children, London, UK.ORCID http://orcid.org/0000-0001-6299-9866

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Haemolytic Uraemic Syndrome (HUS) is a rare medical condition characterised by microangiopathic haemolytic anaemia, thrombocytopenia, and acute kidney injury. Neurological complications are documented but rarely involve the cerebellum. We present a unique case of a 23-month-old male with HUS triggered by Escherichia coli-O157 (E.coli-O157) infection leading to an isolated cerebellar stroke.The patient initially presented with fever, bloody stools, and seizures. Confirmation of E.coli-O157 infection was obtained, and MRI revealed an isolated cerebellar stroke. Treatment included supportive care, anticoagulation for a right atrial thrombus, with gradual improvement observed.This case highlights the unusual occurrence of isolated cerebellar stroke in HUS patients, emphasising the importance of promptly recognizing manifestations of the central nervous system and the necessity for a multidisciplinary approach. Finally, a comprehensive literature review was conducted to identify cases of HUS patients with cerebellar involvement.

Indexed as

Hemolytic-Uremic SyndromeCerebellar DiseasesDiagnosis, DifferentialEscherichia coli InfectionsEscherichia coli O157HumansInfantMagnetic Resonance ImagingMaleStroke1Cerebellum2Posterior-Inferior Cerebellar Artery3PICA4HUS5Case report6Ischaemic injury

Identifiers

PMID38926183
PMCPMC11424696

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.