Evidence map›Paper›PMID 38925989›Full record

ArticleEndocrine journal2024

Preoperative hemoglobin A1c is associated with postoperative bleeding after vitrectomy for vitreous hemorrhage in patients with diabetic retinopathy.

Saori Motoda, Masanori Kanai, Susumu Sakimoto, Harutoshi Ozawa, Chisaki Ishibashi, Shingo Fujita, Yoshiya Hosokawa, Megu Y Baden, Yukari Fujita, Takekazu Kimura and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Endocrine journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Saori MotodaDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Masanori KanaiDepartment of Ophthalmology, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Susumu SakimotoDepartment of Ophthalmology, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Harutoshi OzawaDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Chisaki IshibashiDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Shingo FujitaDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Yoshiya HosokawaDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Megu Y BadenDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Yukari FujitaDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Takekazu KimuraDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Ayumi TokunagaDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Takao NammoDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Kenji FukuiDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Junji KozawaDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Hirokazu SakaguchiDepartment of Ophthalmology, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Kohji NishidaDepartment of Ophthalmology, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Iichiro ShimomuraDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously reported that a high HbA1c level 3 months before vitrectomy for vitreous hemorrhage or a large preoperative decrease in the HbA1c level over 3 months tended to increase the risk of rebleeding in diabetic retinopathy patients evaluated between 2010 and 2014. Here, we aimed to confirm these results with an extended study period and an increased number of operated eyes. This study included 121 diabetic patients who were admitted to Osaka University Hospital between 2010 and 2019 and who underwent vitrectomy for vitreous hemorrhage. Binomial logistic regression analysis was performed with the presence of postoperative bleeding as the outcome. The present study showed that the duration of the operation was associated with rebleeding (odds ratio = 1.02, p = 0.0016). A high HbA1c level just before vitrectomy tended to be associated with the bleeding (odds ratio = 1.27, p = 0.05), while preoperative HbA1c changes were not associated with rebleeding. The results of this study suggest that a high preoperative HbA1c level just before vitrectomy, not a decrease in HbA1c levels, in addition to the duration of the operation may increase the risk of postoperative bleeding after vitrectomy in diabetic retinopathy patients.

Indexed as

Diabetic RetinopathyGlycated HemoglobinPostoperative HemorrhageVitrectomyVitreous HemorrhageAgedFemaleHumansMaleMiddle AgedPreoperative PeriodRetrospective StudiesRisk FactorsGlycated Hemoglobinhemoglobin A1c protein, humanDiabetic retinopathyHemoglobin A1c (HbA1c)Postoperative bleedingVitrectomy

Identifiers

PMID38925989
PMCPMC11778346

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.