Evidence map›Paper›PMID 38925303›Full record

ArticleJournal of affective disorders2024

Pregnancy loss and suicidal behavior: Investigating the mediating role of depressive mood.

D'Andre Walker, Deja Knight, Rebekah Reysen, Katherine Norris

Abstract read
In one paragraph

Article in Journal of affective disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

D'Andre WalkerDepartment of Criminal Justice and Legal Studies, University of Mississippi, United States of America. Electronic address: dlwalke1@olemiss.edu.
Deja KnightDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, United States of America.
Rebekah ReysenCounselor Education Department, Sacred Heart University, United States of America.
Katherine NorrisDepartment of Criminal Justice and Legal Studies, University of Mississippi, United States of America.

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VII Core ProjectU01AG071448 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBERT A HUMMER · 2021 to 2026
$40.2M
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VI Cognition and Early Risk Factors for Dementia ProjectU01AG071450 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI AIELLO, ALLISON E, HUMMER, ROBERT A · 2021 to 2025
$16.2M
NIA NIH HHS U01 AG071448NIA NIH HHS U01 AG071450NICHD NIH HHS P01 HD031921
6 · The paper itself

Abstract

backgroundPregnancy loss is arguably a traumatic and stressful life event that potentially impacts the emotional and behavioral health of those who experience it, especially adolescents. Research assessing this relationship has primarily focused on adult women populations.

methodsUsing data from National Longitudinal Study of Adolescent to Adult Health, a cross-sectional research design was employed to investigate whether pregnancy loss outcomes are associated with depressive mood and suicidal behavior (i.e., suicidal thoughts and suicide attempt) among adolescent girls (N = 6, 913). We also investigated the mediating effect of depressive mood. Initially, an all-encompassing pregnancy loss variable was used, which included abortions and miscarriages. Acknowledging the differences between these pregnancy loss outcomes, we created separate measures for each.

resultsUsing the all-encompassing pregnancy loss variable, findings from logistic regression analyses showed that pregnancy loss is positively and significantly associated with depressive mood and suicidal behaviors. Depressive mood mediated the relationship between pregnancy loss and suicidal behaviors. Miscarriage was positively and significantly associated with suicidal thoughts as well as attempting suicide. Depressive mood mediated the relationship between miscarriage and suicidal thoughts, while only partially mediating the relationship between miscarriage and suicide attempt. No significant effects were observed for abortion on outcomes of interest. LIMITATIONS: Cross-sectional analyses were performed limiting our ability to make casual inferences.

conclusionsPregnancy loss is associated with depressive mood and suicidal behavior, especially among adolescent girls who experience a miscarriage. Adolescent pregnancy and pregnancy loss should remain a focus of scholars and health professionals.

Indexed as

Abortion, SpontaneousDepressionSuicidal IdeationSuicide, AttemptedAdolescentAdultCross-Sectional StudiesFemaleHumansLongitudinal StudiesPregnancyYoung AdultAdolescent pregnancyDepressionMiscarriagePregnancy lossSuicidal behavior

Identifiers

PMID38925303
PMCPMC12887757

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.