Evidence map›Paper›PMID 38925148›Full record

ArticleNature2024

Mechanism for the initiation of spliceosome disassembly.

Matthias K Vorländer, Patricia Rothe, Justus Kleifeld, Eric D Cormack, Lalitha Veleti, Daria Riabov-Bassat, Laura Fin, Alex W Phillips, Luisa Cochella, Clemens Plaschka

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Control of 3' splice site selection by the yeast splicing factor Fyv6.bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Matthias K Vorländer *Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.
Patricia Rothe *Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.
Justus Kleifeld *Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.ORCID 0009-0005-0282-2934
Eric D CormackDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Lalitha VeletiResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.
Daria Riabov-BassatResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.
Laura FinResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.
Alex W PhillipsResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.ORCID 0000-0002-6689-9632
Luisa CochellaResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria. mcochel1@jhmi.edu.ORCID 0000-0003-4018-7722
Clemens PlaschkaResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria. clemens.plaschka@imp.ac.at.ORCID 0000-0002-6020-9514

Funding

Boehringer-Ingelheim Fonds fellowship. L.C.European Research Council 949081Marie Sklodowska-Curie Postdoctoral FellowshipNational Science Foundation
6 · The paper itself

Abstract

Precursor-mRNA (pre-mRNA) splicing requires the assembly, remodelling and disassembly of the multi-megadalton ribonucleoprotein complex called the spliceosome

Indexed as

Caenorhabditis elegansSpliceosomesAnimalsCryoelectron MicroscopyDNA-Binding ProteinsHumansIntronsModels, MolecularRNA-Binding ProteinsRNA HelicasesRNA, MessengerRNA PrecursorsRNA, Small NuclearRNA SplicingRNA Splicing FactorsDHX15 protein, humanDNA-Binding ProteinsGCIP-interacting protein p29, humanRNA-Binding ProteinsRNA HelicasesRNA, MessengerRNA PrecursorsRNA, Small NuclearRNA Splicing FactorsSDE2 protein, humanTFIP11 protein, humanU6 small nuclear RNA

Identifiers

PMID38925148
PMCPMC7616679

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.