ArticleEuropean heart journal. Cardiovascular Imaging2024
Prevalence of asymptomatic valvular heart disease in the elderly population: a community-based echocardiographic study.
Article in European heart journal. Cardiovascular Imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Management of Echocardiography Requests for the Detection and Follow-Up of Heart Valve Disease: A Consensus Statement From the British Heart Valve Society.Clinical cardiology · 2025Guideline
- Pooled it
- Frequency and natural course of American College of Cardiology/American Heart Association valvular heart disease stages in the general population: results from the population-based STAAB cohort study.Heart (British Cardiac Society) · 2026Article
- Clinical Presentation and Management of Patients Referred for Transthoracic Echocardiography in Canada's Arctic Region.CJC open · 2026Article
- Multimodal Fusion of Echocardiogram Images and Electronic Medical Records for Heart Disease Screening: Retrospective Algorithm Development and Validation Study.JMIR medical informatics · 2026Article
- Social Disconnection, Genetic Risk, and the Incidence of Degenerative Valvular Heart Disease: A Population-Based Cohort Study.Journal of the American Heart Association · 2026Article
- Cardiac-related symptoms in individuals aged ≥65 years without diagnosed cardiac disease: insights from the NORSCREEN trial.European heart journal open · 2026Article
- Hypertension and Valvular Heart Disease: An Overview of a Complex and Clinically Meaningful Relationship.Life (Basel, Switzerland) · 2026Review
- Epidemiology and Mortality of Valvular Heart Disease in Brazilian Adults: Findings from the ELSA-Brasil Cohort.Arquivos brasileiros de cardiologia · 2026Article
- 4D Flow MRI Velocity and Turbulence Mapping in Mild Valvular Heart Disease.Journal of magnetic resonance imaging : JMRI · 2026Observational
- Prevalence, Clinical Correlates, and Prognostic Impact of Tricuspid Regurgitation in Older Adults: The ARIC Study.Journal of the American Heart Association · 2025Article
- Artificial intelligence-enhanced electrocardiography to predict regurgitant valvular heart diseases: an international study.European heart journal · 2025Article
- SPEED-TR: a self-distilled and pre-trained transformer model for enhanced ECG detection of tricuspid regurgitation.NPJ digital medicine · 2025Article
- Article
- One-Stop Mitral Valve Transcatheter Edge-to-Edge Repair and Left Atrial Appendage Occlusion in Patients with Atrial Fibrillation and Mitral Regurgitation: A Systematic Review and Meta-Analysis.Journal of personalized medicine · 2025Review
- Incidence and Pathology of Aortic Regurgitation.Interventional cardiology (London, England) · 2025Review
- Global, Regional, and National Burden of Valvular Heart Disease, 1990 to 2021.Journal of the American Heart Association · 2024Article
- Heart valve clinics: an expanding role for the clinical scientists - validation of a framework for competency and certificationOpen heart · 2024Article
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Abstract
aimsWith an ageing population, the presence of asymptomatic valvular heart disease (VHD) in the community remains unknown. The aim of this study is to determine the prevalence and associated factors of asymptomatic VHD in individuals ≥60 years old and to evaluate the feasibility of echocardiographic screening for VHD in this population. METHODS AND
resultsThis was a prospective cohort study conducted between 2007 and 2016 in the UK. Asymptomatic patients with no prior indication for echocardiography were invited to participate and evaluated with a health questionnaire, clinical examination, and transthoracic echocardiography. A total of 10,000 individuals were invited through their general practices. A total of 5429 volunteered to participate, of whom 4237 were eligible for inclusion. VHD was diagnosed in more than a quarter of patients (28.2%). The most common types of VHD were regurgitation of the tricuspid (13.8%), mitral (12.8%), and aortic (8.3%) valves (trivial regurgitation was not included). The rate of prevalence of clinically significant VHD was 2.4% (2.2% moderate and 0.2% severe), with mitral and aortic regurgitation being the most common. The only parameter associated with significant VHD was age (odds ratio 1.07 per 1 year increment, 95% confidence interval 1.05-1.09, P < 0.001). The number needed to scan to diagnose one clinically significant case of VHD is 42 for individuals ≥60 and 15 for those ≥75 years old.
conclusionAsymptomatic VHD is present in a significant proportion of otherwise healthy individuals without known VHD over 60 years old. Age is strongly associated with an increased incidence of significant VHD.
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