Evidence map›Paper›PMID 38924775›Full record

ArticleAmerican journal of respiratory and critical care medicine2024

Single-Cell Analysis Reveals Novel Immune Perturbations in Fibrotic Hypersensitivity Pneumonitis.

Amy Y Zhao, Avraham Unterman, Nebal S Abu Hussein, Prapti Sharma, Fadi Nikola, Jasper Flint, Xiting Yan, Taylor S Adams, Aurelien Justet, Tomokazu S Sumida and 15 more

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
  2. CD14Genes & diseases · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Immunological mechanisms and therapeutic approaches in pulmonary fibrosis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
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  20. Article
4 · The record

Corrections and comments

  • Commented on by
    GZM2024
5 · Who and what money

Authors and funding

25 authors.

Amy Y ZhaoSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.ORCID 0000-0003-0481-2885
Avraham UntermanSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.ORCID 0000-0003-0965-3326
Nebal S Abu HusseinSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.
Prapti SharmaSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.
Fadi NikolaSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.
Jasper FlintSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.
Xiting YanSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.ORCID 0000-0001-8688-9004
Taylor S AdamsSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.
Aurelien JustetSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.
Tomokazu S SumidaDepartment of Neurology.
Jiayi ZhaoSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.
Jonas C SchuppSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.
Micha Sam B RaredonSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.
Farida AhangariSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.ORCID 0000-0002-4144-9395
Giuseppe DeluliisSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.
Yingze ZhangDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Ivette Buendia-RoldanInstituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico.
Ayodeji AdegunsoyeSection of Pulmonary/Critical Care, Department of Medicine, University of Chicago, Chicago, Illinois.
Anne I SperlingDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, Charlottesville, Virginia.
Antje PrasseSection of Pulmonary Medicine, University Medical Center, Basel, Switzerland; and.
Changwan RyuSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.ORCID 0000-0001-6211-4327
Erica HerzogSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.
Moises SelmanInstituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico.
Annie PardoUniversidad Nacional Autónoma de México, Mexico City, Mexico.
Naftali KaminskiSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.ORCID 0000-0001-5917-4601

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Medical Scientist Training ProgramT32GM136651 · NIGMS · YALE UNIVERSITY · PI BARBARA I KAZMIERCZAK · 2020 to 2026
$16.5M
Genomic Analysis of Tissue and Cellular Heterogeneity in IPFR01HL127349 · NHLBI · YALE UNIVERSITY · PI BENOS, PANAGIOTIS V, KAMINSKI, NAFTALI · 2015 to 2025
$5.9M
Research Training in AnesthesiaT32GM086287 · NIGMS · YALE UNIVERSITY · PI ROBERT SCHONBERGER · 2009 to 2026
$3.7M
Noradrenergic mechanisms of IPFR01HL163984 · NHLBI · YALE UNIVERSITY · PI Erica L Herzog · 2022 to 2026
$3.7M
Epithelial Protective Effects of Thyroid Hormone Signaling in FibrosisR01HL141852 · NHLBI · YALE UNIVERSITY · PI KAMINSKI, NAFTALI · 2019 to 2022
$3.4M
Normal Aging Lung Cell Atlas (NALCA)U01HL145567 · NHLBI · YALE UNIVERSITY · PI KAMINSKI, NAFTALI · 2019 to 2022
$2.8M
Macrophage driven, profibrotic adrenergic nerve remodeling in SSc-ILDR01HL152677 · NHLBI · YALE UNIVERSITY · PI HERZOG, ERICA L · 2020 to 2023
$2.4M
Graph Learning of Cell-cell Communications in Spatial TranscriptomicsR01LM014087 · NLM · YALE UNIVERSITY · PI WANG, ZUOHENG, YAN, XITING · 2022 to 2025
$1.5M
Mitochondrial DNA and TLR9 in Pulmonary FibrosisK08HL151970 · NHLBI · YALE UNIVERSITY · PI RYU, CHANGWAN · 2020 to 2024
$840k
Improving Pulmonary Fibrosis Classification with Genomics Informed Phenotypic ClustersK23HL146942 · NHLBI · UNIVERSITY OF CHICAGO · PI ADEGUNSOYE, AYODEJI · 2020 to 2024
$810k
Deep and Integrative Analysis of RNA Sequencing Data to Identify Pathogenesis Heterogeneity of Chronic Lung DiseaseR21LM012884 · NLM · YALE UNIVERSITY · PI YAN, XITING · 2018 to 2019
$415k
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS 1K08HL151970-01NHLBI NIH HHS F30 HL162459NHLBI NIH HHS K08 HL151970NHLBI NIH HHS K23 HL146942NHLBI NIH HHS R01 HL127349NHLBI NIH HHS R01 HL141852NHLBI NIH HHS R01 HL152677NHLBI NIH HHS R01 HL163984NHLBI NIH HHS R21 HL161723NHLBI NIH HHS U01 HL145567NIGMS NIH HHS T32 GM086287NIGMS NIH HHS T32GM086287NIGMS NIH HHS T32 GM136651NLM NIH HHS R01 LM014087NLM NIH HHS R21 LM012884Pulmonary Fibrosis FoundationThree Lakes FoundationVeracyte
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alveolitis, Extrinsic AllergicSingle-Cell AnalysisAdultAgedBronchoalveolar Lavage FluidCase-Control StudiesFemaleHumansIdiopathic Pulmonary FibrosisLeukocytes, MononuclearMaleMexicoMiddle AgedMonocytesfibrotic hypersensitivity pneumonitisidiopathic pulmonary fibrosisinterstitial lung diseasesingle-cell RNA sequencingusual interstitial pneumonia

Identifiers

PMID38924775
PMCPMC11568434

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.