Evidence map›Paper›PMID 38924411›Full record

ArticleScience advances2024

Ellen K White, Aayushi Uberoi, Jamie Ting-Chun Pan, Jordan T Ort, Amy E Campbell, Sofia M Murga-Garrido, Jordan C Harris, Preeti Bhanap, Monica Wei, Nelida Y Robles and 2 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. The dual role of the microbiome in chronic wound management.Cell communication and signaling : CCS · 2026
    Review
  4. A Survey of the Microbiome, Culturome and ARG Profile of a Cohort of Chronic Diabetic Foot Lesions.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. What's New in Wound Healing: Treatment Advances and Microbial Insights.American journal of clinical dermatology · 2025
    Review
  14. Article
  15. Skin microbiome and dermatologic disorders.The Journal of clinical investigation · 2025
    Review
  16. Article
  17. Article
  18. Getting wound closure with Alcaligenes.Nature reviews. Microbiology · 2024
    Article
  19. Pressure injuries and biofilms: Microbiome, model systems and therapies.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Review
  20. A structural equation model predicts chronic wound healing time using patient characteristics and wound microbiome composition.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ellen K WhiteDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-8524-7066
Aayushi UberoiDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-6250-6133
Jamie Ting-Chun PanDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0009-0005-9778-1361
Jordan T OrtDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-6977-4168
Amy E CampbellDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-3676-2253
Sofia M Murga-GarridoDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-4527-9407
Jordan C HarrisDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Preeti BhanapDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0009-0005-8711-9972
Monica WeiDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Nelida Y RoblesDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-1311-7609
Sue E GardnerCollege of Nursing, The University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0001-6224-6944
Elizabeth A GriceDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-3939-2200

Funding

Penn Dermatology Research Training ProgramT32AR007465 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI Elizabeth Anne Grice, David Joel Margolis · 1986 to 2026
$9.0M
Study Design and Data AnalysisP30AR069589 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI Elizabeth Anne Grice · 2016 to 2026
$8.6M
UPenn Post Baccalaureate Research Education Program.R25GM071745 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BHOJ, ELIZABETH JOYCE, KESSLER, DANIEL S · 2005 to 2024
$6.4M
Decoding the microbial burden in diabetic foot ulcersR01NR015639 · NINR · UNIVERSITY OF PENNSYLVANIA · PI GRICE, ELIZABETH ANNE · 2015 to 2023
$4.1M
Bioburden Predictors of Diabetic Ulcer ComplicationsR01NR009448 · NINR · UNIVERSITY OF IOWA · PI GARDNER, SUE E · 2007 to 2011
$2.9M
Training in Microbial Pathogenesis and GenomicsT32AI141393 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI GOULIAN, MARK D, ZHU, JUN · 2019 to 2023
$1.3M
Decoding microbial-Aryl Hydrocarbon Receptor interactions at the skin barrier interfaceK99AR081404 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI UBEROI, AAYUSHI · 2022 to 2023
$181k
Skin microbial-based mechanisms of accelerated wound healingF31AR079852 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI WHITE, ELLEN · 2022 to 2023
$49k
The trigger and homeostatic function of a novel immune-sebum circuitF31AR079845 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI HARRIS, JORDAN · 2022 to 2023
$41k
NIAID NIH HHS T32 AI141393NIAMS NIH HHS F31 AR079845NIAMS NIH HHS F31 AR079852NIAMS NIH HHS K99 AR081404NIAMS NIH HHS P30 AR069589NIAMS NIH HHS T32 AR007465NIGMS NIH HHS R25 GM071745NINR NIH HHS R01 NR009448NINR NIH HHS R01 NR015639
6 · The paper itself

Abstract

Chronic wounds are a common and costly complication of diabetes, where multifactorial defects contribute to dysregulated skin repair, inflammation, tissue damage, and infection. We previously showed that aspects of the diabetic foot ulcer microbiota were correlated with poor healing outcomes, but many microbial species recovered remain uninvestigated with respect to wound healing. Here, we focused on

Indexed as

Alcaligenes faecalisKeratinocytesMatrix MetalloproteinasesWound HealingAnimalsDiabetic FootHumansMaleMiceRe-EpithelializationMatrix Metalloproteinases

Identifiers

PMID38924411
PMCPMC11204295

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.