Evidence map›Paper›PMID 38924400›Full record

ArticleScience advances2024

The child who lived: Down syndrome among Neanderthals?

Mercedes Conde-Valverde, Amara Quirós-Sánchez, Julia Diez-Valero, Nieves Mata-Castro, Alfredo García-Fernández, Rolf Quam, José Miguel Carretero, Rebeca García-González, Laura Rodríguez, Ángeles Sánchez-Andrés and 3 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The history of Down syndrome-associated Alzheimer's disease; past, present, and future.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mercedes Conde-ValverdeUniversidad de Alcalá, Departamento de Ciencias de la Vida, Cátedra de Otoacústica Evolutiva y Paleoantropología (HM Hospitales-Universidad de Alcalá), Alcalá de Henares, Spain.ORCID 0000-0003-1891-5324
Amara Quirós-SánchezUniversidad de Alcalá, Departamento de Ciencias de la Vida, Cátedra de Otoacústica Evolutiva y Paleoantropología (HM Hospitales-Universidad de Alcalá), Alcalá de Henares, Spain.ORCID 0009-0004-0922-2053
Julia Diez-ValeroUniversidad de Alcalá, Departamento de Ciencias de la Vida, Cátedra de Otoacústica Evolutiva y Paleoantropología (HM Hospitales-Universidad de Alcalá), Alcalá de Henares, Spain.ORCID 0009-0007-3945-5351
Nieves Mata-CastroUniversidad de Alcalá, Departamento de Ciencias de la Vida, Cátedra de Otoacústica Evolutiva y Paleoantropología (HM Hospitales-Universidad de Alcalá), Alcalá de Henares, Spain.ORCID 0000-0002-5356-290X
Alfredo García-FernándezUniversidad de Alcalá, Departamento de Ciencias de la Vida, Cátedra de Otoacústica Evolutiva y Paleoantropología (HM Hospitales-Universidad de Alcalá), Alcalá de Henares, Spain.ORCID 0000-0002-6019-1844
Rolf QuamUniversidad de Alcalá, Departamento de Ciencias de la Vida, Cátedra de Otoacústica Evolutiva y Paleoantropología (HM Hospitales-Universidad de Alcalá), Alcalá de Henares, Spain.ORCID 0000-0002-1140-5615
José Miguel CarreteroCentro de Investigación UCM-ISCIII sobre la Evolución y Comportamiento Humanos, Madrid, Spain.ORCID 0000-0003-0409-8087
Rebeca García-GonzálezLaboratorio de Evolución Humana, Universidad de Burgos, Burgos, Spain.ORCID 0000-0002-1035-6655
Laura RodríguezLaboratorio de Evolución Humana, Universidad de Burgos, Burgos, Spain.ORCID 0000-0002-5090-1582
Ángeles Sánchez-AndrésUniversidad de Alcalá, Departamento de Ciencias de la Vida, Cátedra de Otoacústica Evolutiva y Paleoantropología (HM Hospitales-Universidad de Alcalá), Alcalá de Henares, Spain.ORCID 0000-0001-5159-3246
Juan Luis ArsuagaCentro de Investigación UCM-ISCIII sobre la Evolución y Comportamiento Humanos, Madrid, Spain.ORCID 0000-0001-5361-2295
Ignacio MartínezUniversidad de Alcalá, Departamento de Ciencias de la Vida, Cátedra de Otoacústica Evolutiva y Paleoantropología (HM Hospitales-Universidad de Alcalá), Alcalá de Henares, Spain.ORCID 0000-0002-1835-9199
Valentín VillaverdeUniversitat de València, Departament de Prehistòria, Arqueologia i Història Antiga (PREMEDOC), Av. Blasco Ibañez 28, 46010 València, Spain.ORCID 0000-0002-2876-0306

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caregiving for disabled individuals among Neanderthals has been known for a long time, and there is a debate about the implications of this behavior. Some authors believe that caregiving took place between individuals able to reciprocate the favor, while others argue that caregiving was produced by a feeling of compassion related to other highly adaptive prosocial behaviors. The study of children with severe pathologies is particularly interesting, as children have a very limited possibility to reciprocate the assistance. We present the case of a Neanderthal child who suffered from a congenital pathology of the inner ear, probably debilitating, and associated with Down syndrome. This child would have required care for at least 6 years, likely necessitating other group members to assist the mother in childcare.

Indexed as

Down SyndromeNeanderthalsAnimalsChildChild, PreschoolFemaleHumansMale

Identifiers

PMID38924400
PMCPMC11204207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.