Evidence map›Paper›PMID 38924394›Full record

ArticleScience advances2024

Optogenetic β cell interrogation in vivo reveals a functional hierarchy directing the Ca

Luis Fernando Delgadillo-Silva, Emirhan Tasöz, Sumeet Pal Singh, Prateek Chawla, Eleni Georgiadou, Anne Gompf, Guy A Rutter, Nikolay Ninov

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luis Fernando Delgadillo-SilvaCentre for Regenerative Therapies TU Dresden, Dresden 01307, Germany.ORCID 0000-0002-2721-5920
Emirhan TasözCentre for Regenerative Therapies TU Dresden, Dresden 01307, Germany.ORCID 0000-0003-2025-3366
Sumeet Pal SinghIRIBHM, Université Libre de Bruxelles (ULB), Brussels, Belgium.ORCID 0000-0002-5154-3318
Prateek ChawlaCentre for Regenerative Therapies TU Dresden, Dresden 01307, Germany.
Eleni GeorgiadouSection of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Faculty of Medicine, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London W12 ONN, UK.
Anne GompfCentre for Regenerative Therapies TU Dresden, Dresden 01307, Germany.
Guy A RutterCardiometabolic Axis, CR-CHUM, and University of Montreal, Montreal, QC, Canada; 1IRIBHM, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.ORCID 0000-0001-6360-0343
Nikolay NinovCentre for Regenerative Therapies TU Dresden, Dresden 01307, Germany.ORCID 0000-0003-3286-6100

Funding

Control of insulin secretion by mitochondrial fusionR01DK135268 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Brett A Kaufman, Scott Soleimanpour · 2023 to 2026
$2.4M
NIDDK NIH HHS R01 DK135268Wellcome Trust
6 · The paper itself

Abstract

Coordination of cellular activity through Ca

Indexed as

CalciumGlucoseInsulin-Secreting CellsOptogeneticsZebrafishAnimalsCalcium SignalingCalciumGlucose

Identifiers

PMID38924394
PMCPMC11204215

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.