Evidence map›Paper›PMID 38924169›Full record

Trial reportJournal of advanced nursing2025

Integrated pulmonary index during procedural sedation and analgesia: A cluster-randomized trial.

Aaron Conway, Mohammad Goudarzi Rad, Kristina Chang, Matteo Parotto, Sebastian Mafeld

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of advanced nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05068700 (A Parallel Cluster-randomized Trial of the Integrated Pulmonary Index for Nurse-administered Procedural Sedation), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05068700 nacompletednot on this map

A Parallel Cluster-randomized Trial of the Integrated Pulmonary Index for Nurse-administered Procedural Sedation

TypeinterventionalSponsorUniversity Health Network, TorontoRan2022 to 2023Enrolled401ConditionsConscious Sedation, Nursing, AnaesthesiaArmsIntegrated Pulmonary Index, Standard capnography monitoring
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aaron ConwaySchool of Nursing, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0002-9583-8636
Mohammad Goudarzi RadLawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-2609-8611
Kristina ChangLawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.
Matteo ParottoDepartment of Anesthesiology and Pain Medicine and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada.
Sebastian MafeldJoint Department of Medical Imaging, University Health Network, Toronto, Ontario, Canada.

Funding

Medtronic
6 · The paper itself

Abstract

aimTo evaluate the effectiveness of utilizing the integrated pulmonary index for capnography implementation during sedation administered by nurses.

designCluster-randomized trial.

methodsParticipants were enrolled from the interventional radiology department at an academic hospital in Canada. Nurses were randomized to either enable or disable the Integrated Pulmonary Index feature of the capnography monitor. Procedures were observed by a research assistant to collect information about alarm performance characteristics. The primary outcome was the number of seconds in an alert condition state without an intervention being applied.

resultsThe number of seconds in an alarm state without intervention was higher in the group that enabled the integrated pulmonary index compared to the group that disabled this feature, but this difference did not reach statistical significance. Likewise, the difference between groups for the total alarm duration, total number of alarms and the total number of appropriate alarms was not statistically significant. The number of inappropriate alarms was higher in the group that enabled the Integrated Pulmonary Index, but this estimate was highly imprecise. There was no difference in the odds of an adverse event (measured by the Tracking and Reporting Outcomes of Procedural Sedation tool) occurring between groups. Desaturation events were uncommon and brief in both groups but the area under the SpO

conclusionEnabling the integrated pulmonary index during nurse-administered procedural sedation did not reduce nurses' response times to alarms. Therefore, integrating multiple physiological parameters related to respiratory assessment into a single index did not lower the threshold for intervention by nurses. IMPLICATIONS FOR THE PROFESSION AND/OR PATIENT CARE: The time it takes to respond to capnography monitor alarms will not be reduced if the integrated pulmonary Iindex feature of capnography monitors is enabled during nurse-administered procedural sedation. IMPACT: Results do not support the routine enabling of the integrated pulmonary index when nurses use capnography to monitor patients during procedural sedation as a strategy to reduce the time it takes to initiate responses to alarms. REPORTING

methodCONSORT. PATIENT OR PUBLIC CONTRIBUTION: There was no patient or public contribution.

trial registrationThis study was prospectively registered at ClinicalTrials.gov (ID: NCT05068700).

Indexed as

AnalgesiaCapnographyProcedural SedationAdultAgedCanadaFemaleHumansMaleMiddle AgedMonitoring, Physiologicalarm fatiguealarm managementcapnographycluster‐randomized trialintegrated pulmonary indexnursingphysiological monitoringprocedural sedationsedation

Identifiers

PMID38924169
PMCPMC12371815

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.