Evidence map›Paper›PMID 38923786›Full record

ArticleJournal of applied clinical medical physics2024

Exploring feasibility criteria for stereotactic radiosurgical treatment of multiple brain metastases using five linac machines.

Yusuke Sakai, Kazuki Kubo, Hajime Monzen, Yoshihiro Ueda, Masao Tanooka, Masayoshi Miyazaki, Kentaro Ishii, Ryu Kawamorita

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. A predictive model for Gamma Knife intermediate dose spill: R50%Journal of applied clinical medical physics · 2025
    Article
  4. Article
  5. A dosimetric and treatment delivery comparisons of the Halcyon and TrueBeam stereotactic plans for one or more brain metastases.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yusuke SakaiDepartment of Medical Physics, Graduate School of Medical Sciences, Kindai University, Osakasayama, Osaka, Japan.
Kazuki KuboDepartment of Medical Physics, Graduate School of Medical Sciences, Kindai University, Osakasayama, Osaka, Japan.
Hajime MonzenDepartment of Medical Physics, Graduate School of Medical Sciences, Kindai University, Osakasayama, Osaka, Japan.ORCID https://orcid.org/0000-0001-7745-9379
Yoshihiro UedaDepartment of Radiation Oncology, Osaka International Cancer Institute, Chuo-ku, Osaka, Japan.
Masao TanookaDepartment of Radiotherapy, Takarazuka City Hospital, Takarazuka, Hyogo, Japan.
Masayoshi MiyazakiDepartment of Radiation Oncology, Osaka International Cancer Institute, Chuo-ku, Osaka, Japan.
Kentaro IshiiDepartment of Radiation Oncology, Tane General Hospital, Nishi-ku, Osaka, Japan.
Ryu KawamoritaDepartment of Radiation Oncology, Tane General Hospital, Nishi-ku, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to find descriptors that correlates with normal brain dose to determine the feasibility of performing fractionated stereotactic radiosurgery (SRS) for multiple brain metastases (BMs) using five linac machines.

methodsThirty-two patients with 1-30 BMs were enrolled. Treatment plans were created using TrueBeam, Novalis Tx, TrueBeam Edge, Halcyon, and Tomotherapy linacs. The sum of all planning target volumes (PTVs) was defined as PTV

resultsCorrelations between each characteristic and normal brain dose were statistically significant (p < 0.05) across all machines. The correlation coefficients between each characteristic and V

conclusionThis study devised fractionated SRS plans using for 1-30 BMs across five linac machines to find descriptors for determining SRS feasibility based on normal brain dose. TSA proved to be a promising descriptor of SRS feasibility for treating multiple BMs.

Indexed as

Brain NeoplasmsFeasibility StudiesParticle AcceleratorsRadiosurgeryRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedFemaleHumansMaleOrgans at RiskPrognosisbrain metastasisSRSsurface areaVMAT

Identifiers

PMID38923786
PMCPMC11492394

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.