Evidence map›Paper›PMID 38923780›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

High-Precision Photoacoustic Neural Modulation Uses a Non-Thermal Mechanism.

Guo Chen, Feiyuan Yu, Linli Shi, Carolyn Marar, Zhiyi Du, Danchen Jia, Ji-Xin Cheng, Chen Yang

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. A flexible photoacoustic retinal prosthesis.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. High-Precision Photoacoustic Neural Modulation Uses a Non-Thermal Mechanism.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Guo ChenDepartment of Electrical and Computer Engineering, Boston University, Boston, MA, 02215, USA.ORCID 0000-0003-0239-0068
Feiyuan YuDepartment of Electrical and Computer Engineering, Boston University, Boston, MA, 02215, USA.
Linli ShiDepartment of Chemistry, Boston University, Boston, MA, 02215, USA.
Carolyn MararDepartment of Biomedical Engineering, Boston University, Boston, MA, 02215, USA.
Zhiyi DuDepartment of Chemistry, Boston University, Boston, MA, 02215, USA.
Danchen JiaDepartment of Electrical and Computer Engineering, Boston University, Boston, MA, 02215, USA.
Ji-Xin ChengDepartment of Electrical and Computer Engineering, Boston University, Boston, MA, 02215, USA.ORCID 0000-0002-5607-6683
Chen YangDepartment of Electrical and Computer Engineering, Boston University, Boston, MA, 02215, USA.ORCID 0000-0001-9454-847X

Funding

Unveiling the mechanisms of ultrasound neuromodulation via spatially confined stimulation and temporally resolved recordingR01NS109794 · NINDS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI CHENG, JI-XIN, HAN, XUE · 2018 to 2022
$3.6M
NINDS NIH HHS R01 NS109794
6 · The paper itself

Abstract

Neuromodulation is a powerful tool for fundamental studies in neuroscience and potential treatments of neurological disorders. Both photoacoustic (PA) and photothermal (PT) effects are harnessed for non-genetic high-precision neural stimulation. Using a fiber-based device excitable by a nanosecond pulsed laser and a continuous wave laser for PA and PT stimulation, respectively, PA and PT neuromodulation is systematically investigated at the single neuron level. These results show that to achieve the same level of neuron activation recorded by Ca

Indexed as

NeuronsPhotoacoustic TechniquesAnimalsLasersMicePatch-Clamp Techniquesion channelsneuromodulationpatch clampphotoacoustic

Identifiers

PMID38923780
PMCPMC11348214

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.