Evidence map›Paper›PMID 38923767›Full record

ArticleInfluenza and other respiratory viruses2024

How Does the Burden of Respiratory Syncytial Virus Compare to Influenza in Spanish Adults?

Federico Martinón-Torres, Clara Gutierrez, Ana Cáceres, Karin Weber, Antoni Torres

Abstract readComparative Study
In one paragraph

Article in Influenza and other respiratory viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  13. Hospitalisation due to respiratory syncytial virus in a population-based cohort of older adults in Spain, 2016/17 to 2019/20.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Federico Martinón-TorresTranslational Pediatrics and Infectious Diseases, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain.ORCID 0000-0002-9023-581X
Clara GutierrezInfectious Diseases and Vaccines, Janssen-Cilag, Madrid, Spain.
Ana CáceresInfectious Diseases and Vaccines, Janssen-Cilag, Madrid, Spain.
Karin WeberGlobal Medical Affairs IDV, Janssen-Cilag, Vienna, Austria.
Antoni TorresConsorcio Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.

Funding

Fondo de Investigación Sanitaria PI070069/PI1000540/PI1601569/PI1901090/PI22/00406Fondo Europeo de Desarrollo Regional (FEDER)Instituto de Salud Carlos IIIJanssen Pharmaceuticals
6 · The paper itself

Abstract

backgroundRespiratory syncytial virus (RSV) and influenza infections cause significant annual morbidity and mortality worldwide in at-risk populations. This study is aimed at assessing hospital burden and healthcare resource utilization (HRU) of RSV and influenza in adults in Spain.

methodsData were obtained from the Projected Hospitalisation Database of inpatient episodes (ages: younger adults 18-50 and 51-64 years; older adults 65-74, 75-84, and ≥ 85 years) during 2015, 2017, and 2018 in Spanish public hospitals. Incidence, mean hospitalization, and HRU assessments, including length of stay (LOS), intensive care unit (ICU) usage, and age-standardized mortality rates, were collected and stratified by age group, with analyses focusing on the adult population (≥ 18 years old).

resultsMean hospitalization rate in the population across all years was lower in individuals with RSV versus influenza (7.2/100,000 vs. 49.7/100,000 individuals). ICU admissions and median LOS were similar by age group for both viruses. Age-standardized mortality was 6.3/100,000 individuals and 6.1/100,000 individuals in patients with RSV and influenza, respectively, and mortality rates were similar in older adults (≥ 65 years) for both viruses.

conclusionsRSV and influenza infection were associated with considerable HRU. There is a substantial disease burden for RSV infection in older adults ≥ 65 years. While RSV hospitalization rates in adults reported here appeared lower than influenza, RSV is still underdiagnosed in the hospital setting and its incidence might be similar to, or higher than, influenza.

Indexed as

HospitalizationInfluenza, HumanRespiratory Syncytial Virus InfectionsAdolescentAdultAgedAged, 80 and overCost of IllnessFemaleHumansIncidenceIntensive Care UnitsLength of StayMaleMiddle AgedRespiratory Syncytial Virus, Humanburden of diseaseepidemiologyhospitalizationhumaninfluenzarespiratory syncytial virus

Identifiers

PMID38923767
PMCPMC11194680

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.