Evidence map›Paper›PMID 38923462›Full record

ArticleCell reports2024

Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance.

Flavio R Palma, Diego R Coelho, Kirthi Pulakanti, Marcelo J Sakiyama, Yunping Huang, Fernando T Ogata, Jeanne M Danes, Alison Meyer, Cristina M Furdui, Douglas R Spitz and 5 more

Abstract readPublished Erratum
In one paragraph

Article in Cell reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Flavio R Palma
Diego R Coelho
Kirthi Pulakanti
Marcelo J Sakiyama
Yunping Huang
Fernando T Ogata
Jeanne M Danes
Alison Meyer
Cristina M Furdui
Douglas R Spitz
Ana P Gomes
Benjamin N Gantner
Sridhar Rao
Vadim Backman
Marcelo G Bonini

Funding

A redox-sensitive switch in the macrophage nucleus regulates acute phaseinflammatory injuryR01HL163820 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BONINI, MARCELO G., GANTNER, BENJAMIN N. · 2022 to 2025
$2.3M
H3 histone oxidation is a new posttranslational modification linking heavy metal-induced metabolic changes and oncegenic epigenetic reprogrammingR01ES035723 · NIEHS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Marcelo G. Bonini · 2024 to 2026
$1.2M
Suppression of progesterone receptor signaling by heavy metals promotes tamoxifen resistance and metastasis or ER+ breast cancerR01ES035353 · NIEHS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BONINI, MARCELO G. · 2024 to 2025
$934k
Arsenic suppresses progesterone receptor signaling and promotes tamoxifen resistance and metastasis of ER+ breast cancerR56ES033398 · NIEHS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BONINI, MARCELO G. · 2022 to 2022
$150k
NHLBI NIH HHS R01 HL163820NIEHS NIH HHS R01 ES035353NIEHS NIH HHS R01 ES035723NIEHS NIH HHS R56 ES033398
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID38923462
PMCPMC11560056

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.