Evidence map›Paper›PMID 38923346›Full record

ReviewThoracic cancer2024

The immune microenvironment of lung adenocarcinoma featured with ground-glass nodules.

Changtai Zhao, Rongxin Xiao, Hongming Jin, Xiao Li

Abstract readReview
In one paragraph

Review in Thoracic cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Changtai ZhaoDepartment of Thoracic Surgery, Thoracic Oncology Institute, Peking University People's Hospital, Beijing, China.ORCID 0000-0003-4194-1205
Rongxin XiaoDepartment of Thoracic Surgery, Thoracic Oncology Institute, Peking University People's Hospital, Beijing, China.ORCID 0000-0002-0880-093X
Hongming JinDepartment of Thoracic Surgery, Thoracic Oncology Institute, Peking University People's Hospital, Beijing, China.
Xiao LiDepartment of Thoracic Surgery, Thoracic Oncology Institute, Peking University People's Hospital, Beijing, China.

Funding

National Natural Science Foundation of China 92059203The Beijing Municipal Program Project of Collaborative Research on Major and Difficult Diseases by Integrating Traditional Chinese Medicine and Western Medicine 2023BJSZDYNJBXTGG-012
6 · The paper itself

Abstract

Early-stage lung cancer is now more commonly identified in the form of ground-glass nodules (GGNs). Presently, the treatment of lung cancer with GGNs mainly depends on surgery; however, issues still exist such as overtreatment and delayed treatment due to the nonuniform standard of follow-up. Therefore, the discovery of a noninvasive treatment could expand the treatment repertoire of ground-glass nodular lung cancer and benefit the prognosis of patients. Immunotherapy has recently emerged as a new promising approach in the field of lung cancer treatment. Thus, this study presents a comprehensive review of the immune microenvironment of lung cancer with GGNs and describes the functions and characteristics of various immune cells involved, aiming to provide guidance for the clinical identification of novel immunotherapeutic targets.

Indexed as

Adenocarcinoma of LungLung NeoplasmsTumor MicroenvironmentHumansB cellground‐glass noduleslung adenocarcinomaT celltumor immune microenvironment

Identifiers

PMID38923346
PMCPMC11219292

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.