Evidence map›Paper›PMID 38923314›Full record

ArticleInfluenza and other respiratory viruses2024

Late-Season Influenza Vaccine Effectiveness Against Medically Attended Outpatient Illness, United States, December 2022-April 2023.

Jessie R Chung, Philip Shirk, Manjusha Gaglani, Manohar B Mutnal, Mary Patricia Nowalk, Krissy Moehling Geffel, Stacey L House, Tara Curley, Karen J Wernli, Erika L Kiniry and 14 more

Abstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Influenza Vaccine Effectiveness Against Medically Attended Outpatients Illness, United States, 2023-2024 Season.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Jessie R ChungInfluenza Division, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0001-5205-966X
Philip ShirkInfluenza Division, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Manjusha GaglaniBaylor Scott & White Health, Temple, Texas, USA.
Manohar B MutnalBaylor Scott & White Health, Temple, Texas, USA.
Mary Patricia NowalkDepartment of Family Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-1702-2690
Krissy Moehling GeffelDepartment of Family Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Stacey L HouseDepartment of Emergency Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
Tara CurleyDepartment of Emergency Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
Karen J WernliKaiser Permanente Washington Health Research Institute, Seattle, Washington, USA.
Erika L KiniryKaiser Permanente Washington Health Research Institute, Seattle, Washington, USA.
Emily T MartinDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.ORCID 0000-0002-5771-8895
Ivana A VaughnHenry Ford Health, Detroit, Michigan, USA.ORCID 0000-0002-7201-0289
Vel MuruganBiodesign Center for Personalized Diagnostics, Arizona State University, Tempe, Arizona, USA.ORCID 0000-0002-7368-7742
Efrem S LimBiodesign Center for Fundamental & Applied Microbiomics, Arizona State University, Tempe, Arizona, USA.
Elie SaadeDivision of Infectious Diseases and HIV Medicine, University Hospitals of Cleveland, Cleveland, Ohio, USA.
Kiran FaryarDepartment of Emergency Medicine, University Hospitals of Cleveland, Cleveland, Ohio, USA.
Olivia L WilliamsDuke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Emmanuel B WalterDuke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Ashley M PriceInfluenza Division, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
John R BarnesInfluenza Division, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Juliana DaSilvaInfluenza Division, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Rebecca KondorInfluenza Division, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Sascha EllingtonInfluenza Division, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Brendan FlanneryInfluenza Division, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
RFA-IP-22-004, Platform to Assess Influenza and COVID-19 Vaccine Effectiveness in Underserved Arizona PopulationsU01IP001180 · IP · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI MURUGAN, VEL · 2022 to 2025
$7.9M
RFA-IP-22-004, Evaluating respiratory virus vaccine effectiveness in a large, diverse healthcare systemU01IP001184 · IP · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZIMMERMAN, RICHARD K · 2022 to 2025
$7.9M
RFA-IP-22-004, Multidisciplinary Approach to Understanding Vaccine Efficacy and Transmission of Viral Respiratory Tract Infections in the Real WorldU01IP001182 · IP · WASHINGTON UNIVERSITY · PI HOUSE, STACEY · 2022 to 2025
$7.9M
RFA-IP-22-004, CORVETS - Cleveland Ohio Respiratory Viruses Vaccines Effectiveness across Traditional Risk Factors and Social Determinants of HealthU01IP001181 · IP · UNIVERSITY HOSPITALS OF CLEVELAND · PI SAADE, ELIE · 2022 to 2025
$6.9M
RFA-IP-22-004, Component A _ Credible Effectiveness Measures of Seasonal Influenza, COVID-19 and Other Respiratory Virus Vaccines against Ambulatory Care for Acute Illness in Texas (and Component D).U01IP001189 · IP · BAYLOR RESEARCH INSTITUTE · PI GAGLANI, MANJUSHA · 2022 to 2025
$6.1M
RFA-IP-22-004, Evaluating influenza, SARS-CoV-2, and other respiratory virus vaccine effectiveness in prevention of acute illness in Washington state 2022-2027U01IP001191 · IP · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI WERNLI, KAREN J · 2022 to 2025
$6.1M
RFA-IP-22-004, Michigan-Ford Initiative to Measure Vaccine Effectiveness (MFIVE): Seasonal Influenza, COVID-19 and Respiratory Virus VaccinesU01IP001193 · IP · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARTIN, EMILY TOTH · 2022 to 2025
$6.1M
RFA-IP-22-004, US Platform to Measure Effectiveness of Seasonal Influenza, COVID-19 and other Respiratory Virus Vaccines for the Prevention of Acute Illness in Ambulatory SettingsU01IP001194 · IP · DUKE UNIVERSITY · PI WALTER, EMMANUEL B · 2022 to 2025
$3.5M
Patient Provider Communication Larch SupplementR01CA262015 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI WERNLI, KAREN J · 2021 to 2025
$3.3M
ACL HHS U01IP001180ACL HHS U01IP001181ACL HHS U01IP001182ACL HHS U01IP001184ACL HHS U01IP001191ACL HHS U01IP001193ACL HHS U01IP001194CDC HHSNCATS NIH HHS UL1 TR001857NCI NIH HHS R01 CA262015NCIRD CDC HHS U01 IP001180NCIRD CDC HHS U01 IP001181NCIRD CDC HHS U01 IP001182NCIRD CDC HHS U01 IP001184NCIRD CDC HHS U01 IP001189NCIRD CDC HHS U01 IP001191NCIRD CDC HHS U01 IP001193NCIRD CDC HHS U01 IP001194NIH HHS UL1TR001857US Centers for Disease Control and Prevention Cooperative Agreement 1 U01 IP001180-01US Centers for Disease Control and Prevention Cooperative Agreement 1 U01 IP001181-01US Centers for Disease Control and Prevention Cooperative Agreement 1 U01 IP001182-01US Centers for Disease Control and Prevention Cooperative Agreement 1 U01 IP001184-01US Centers for Disease Control and Prevention Cooperative Agreement 1 U01 IP001189-01US Centers for Disease Control and Prevention Cooperative Agreement 1 U01 IP001191-01US Centers for Disease Control and Prevention Cooperative Agreement 1 U01 IP001193-01US Centers for Disease Control and Prevention Cooperative Agreement 1 U01 IP001194-01
6 · The paper itself

Abstract

backgroundThe 2022-23 US influenza season peaked early in fall 2022.

methodsLate-season influenza vaccine effectiveness (VE) against outpatient, laboratory-confirmed influenza was calculated among participants of the US Influenza VE Network using a test-negative design.

resultsOf 2561 participants enrolled from December 12, 2022 to April 30, 2023, 91 laboratory-confirmed influenza cases primarily had A(H1N1)pdm09 (6B.1A.5a.2a.1) or A(H3N2) (3C.2a1b.2a.2b). Overall, VE was 30% (95% confidence interval -9%, 54%); low late-season activity precluded estimation for most subgroups.

conclusions2022-23 late-season outpatient influenza VE was not statistically significant. Genomic characterization may improve the identification of influenza viruses that circulate postinfluenza peak.

Indexed as

Influenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeInfluenza, HumanInfluenza VaccinesOutpatientsSeasonsVaccine EfficacyAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleHumansInfantInfluenza Vaccinesinfluenzavaccinationvaccine effectiveness

Identifiers

PMID38923314
PMCPMC11194453

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.