Evidence map›Paper›PMID 38923264›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Isl Identifies the Extraembryonic Mesodermal/Allantois Progenitors and is Required for Placenta Morphogenesis and Vasculature Formation.

Zeyue Zhu, Qicheng Zou, Chunxiao Wang, Dixi Li, Yan Yang, Ying Xiao, Yao Jin, Jie Yan, Lina Luo, Yunfu Sun and 1 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Feto-placental blood vessel development.Development (Cambridge, England) · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zeyue ZhuKey Laboratory of Arrhythmia of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Qicheng ZouKey Laboratory of Arrhythmia of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Chunxiao WangKey Laboratory of Arrhythmia of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Dixi LiDepartment of Hematology, Tongji Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Yan YangKey Laboratory of Arrhythmia of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Ying XiaoKey Laboratory of Arrhythmia of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Yao JinKey Laboratory of Arrhythmia of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Jie YanKey Laboratory of Arrhythmia of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Lina LuoKey Laboratory of Arrhythmia of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Yunfu SunShanghai East Hospital, Tongji University School of Medicine, 150 Jimo Road, Shanghai, 200120, China.
Xingqun LiangShanghai East Hospital, Tongji University School of Medicine, 150 Jimo Road, Shanghai, 200120, China.ORCID 0000-0002-3114-7799

Funding

National Fund for Fostering Talents of Basic Science 31071280National Fund for Fostering Talents of Basic Science 81171069National Natural Science Foundation of China 31171393National Natural Science Foundation of China 81370196
6 · The paper itself

Abstract

The placenta links feto-maternal circulation for exchanges of nutrients, gases, and metabolic wastes between the fetus and mother, being essential for pregnancy process and maintenance. The allantois and mesodermal components of amnion, chorion, and yolk sac are derived from extraembryonic mesoderm (Ex-Mes), however, the mechanisms contributing to distinct components of the placenta and regulation the interactions between allantois and epithelium during chorioallantoic fusion and labyrinth formation remains unclear. Isl1 is expressed in progenitors of the Ex-Mes and allantois the Isl1 mut mouse line is analyzed to investigate contribution of Isl1

Indexed as

AllantoisLIM-Homeodomain ProteinsMesodermPlacentaTranscription FactorsAnimalsFemaleMiceMorphogenesisPlacentationPregnancyinsulin gene enhancer binding protein Isl-1LIM-Homeodomain ProteinsTranscription Factorsallantoisextraembryonic mesodermIsl1lineagepregnant maintenance vasculature

Identifiers

PMID38923264
PMCPMC11348239

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.