Evidence map›Paper›PMID 38923174›Full record

ArticleJournal of diabetes2024

Are sodium-glucose cotransporter-2 inhibitors safe adjunctive drugs during insulin therapy in young children with type 1 diabetes? The first case of type 1 diabetes with SLC5A2 mutation.

Mohamad Ahangar Davoodi, Mohammad Ali Daneshmand, Taraneh Rezaei

Abstract readCase ReportsLetter
In one paragraph

Article in Journal of diabetes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mohamad Ahangar DavoodiDepartment of Pediatric Endocrinology, Arak University of Medical Sciences, Clinical Research Development Center of Amirkabir Hospital, Arak, Iran.
Mohammad Ali DaneshmandArak University of Medical Sciences, Teacher of Pathology in Arak Medical School, Arak, Iran.
Taraneh RezaeiStudent Research Committee, Arak University of Medical Sciences, Arak, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Highlights A persistent glycosuria alongside hypoglycemia in pediatric type 1 diabetes mellitus needs further evaluation. Morning hypoglycemia is a limiting side effect of sodium glucose transporter 2 (SGLT2) inhibitors in children younger than 5 years old. SLC5A2 mutation functioning as a SGLT2 inhibitor can result in acceptable range of glycated hemoglobin in younger children and lower required doses of insulin.

Indexed as

Diabetes Mellitus, Type 1Hypoglycemic AgentsInsulinMutationSodium-Glucose Transporter 2Sodium-Glucose Transporter 2 InhibitorsBlood GlucoseChild, PreschoolDrug Therapy, CombinationFemaleGlycated HemoglobinHumansHypoglycemiaMaleBlood GlucoseGlycated HemoglobinHypoglycemic AgentsInsulinSLC5A2 protein, humanSodium-Glucose Transporter 2Sodium-Glucose Transporter 2 Inhibitors

Identifiers

PMID38923174
PMCPMC11200015

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.