Evidence map›Paper›PMID 38923049›Full record

ArticleProtein science : a publication of the Protein Society2024

Fit-for-purpose heterodivalent single-domain antibody for gastrointestinal targeting of toxin B from Clostridium difficile.

Everardo R Rodriguez Rodriguez, Rune Thorbjørn Nordvang, Marcus Petersson, Jakob Kræmmer Haar Rendsvig, Emma Wenzel Arendrup, Monica L Fernández Quintero, Timothy P Jenkins, Andreas H Laustsen, Sandra Wingaard Thrane

Abstract read
In one paragraph

Article in Protein science : a publication of the Protein Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Everardo R Rodriguez RodriguezBactolife A/S, Copenhagen East, Denmark.ORCID 0000-0002-7445-2830
Rune Thorbjørn NordvangBactolife A/S, Copenhagen East, Denmark.ORCID 0009-0003-9099-3316
Marcus PeterssonBactolife A/S, Copenhagen East, Denmark.ORCID 0000-0002-2466-9038
Jakob Kræmmer Haar RendsvigBactolife A/S, Copenhagen East, Denmark.ORCID 0000-0002-4603-9424
Emma Wenzel ArendrupBactolife A/S, Copenhagen East, Denmark.ORCID 0009-0006-5709-9322
Monica L Fernández QuinteroDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.ORCID 0000-0002-6811-6283
Timothy P JenkinsDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.ORCID 0000-0003-2979-5663
Andreas H LaustsenBactolife A/S, Copenhagen East, Denmark.ORCID 0000-0001-6918-5574
Sandra Wingaard ThraneBactolife A/S, Copenhagen East, Denmark.ORCID 0000-0003-2098-2710

Funding

Innovation Fund Denmark 0174-00002BInnovation Fund Denmark 1044-00106B
6 · The paper itself

Abstract

Single-domain antibodies (sdAbs), such as V

Indexed as

Bacterial ProteinsBacterial ToxinsClostridioides difficileSingle-Domain AntibodiesGastrointestinal TractHumansBacterial ProteinsBacterial ToxinsSingle-Domain AntibodiestoxB protein, Clostridium difficileantibodybile salt stabilityClostridium difficiledevelopabilityoral administrationsingle‐domain antibody

Identifiers

PMID38923049
PMCPMC11201815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.