Cleavage of an engulfment peptidoglycan hydrolase by a sporulation signature protease in Clostridioides difficile.
Diogo Martins, Hailee N Nerber, Charlotte G Roughton, Amaury Fasquelle, Anna Barwinska-Sendra, Daniela Vollmer, Joe Gray, Waldemar Vollmer, Joseph A Sorg, Paula S Salgado and 2 more
Article in Molecular microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors.
Diogo MartinsInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.
Hailee N NerberBiology Department, Texas A&M University, College Station, Texas, USA.
Charlotte G RoughtonFaculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Amaury FasquelleInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.
Anna Barwinska-SendraFaculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Daniela VollmerFaculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Joe GrayFaculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Waldemar VollmerFaculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Joseph A SorgBiology Department, Texas A&M University, College Station, Texas, USA.ORCID 0000-0001-7822-2656
Paula S SalgadoFaculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0003-0417-7615
Adriano O HenriquesInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.ORCID 0000-0003-4292-4802
Mónica SerranoInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.ORCID 0000-0003-3335-3219
Funding
Mechanisms of Clostridium difficile spore germinationR01AI116895 · NIAID · TEXAS A&M UNIVERSITY · PI SORG, JOE · 2015 to 2024
$3.9M
Impact of the C. difficile small acid soluble proteins on spore physiologyR01AI172043 · NIAID · TEXAS A&M UNIVERSITY · PI SORG, JOE · 2022 to 2025
$2.5M
Barbour Foundation PhD StudentshipBiotechnology and Biological Sciences Research Council BB/W005557/1Biotechnology and Biological Sciences Research Council BB/W013630/1European Union Marie Sklodowska Curie Innovative Training Networks 642068Fundação para a Ciência e a Tecnologia LISBOA-01-0145-FEDER-007660Fundação para a Ciência e a Tecnologia PD/BD/143148/2019Fundação para a Ciência e a Tecnologia PTDC/BIA-MIC/29293/2017Medical Research Council MR/V032151/1National Institute of Allergy and Infectious Diseases R01AI116895National Institute of Allergy and Infectious Diseases R01AI172043NIAID NIH HHS R01 AI116895NIAID NIH HHS R01 AI172043
6 · The paper itself
Abstract
In the model organism Bacillus subtilis, a signaling protease produced in the forespore, SpoIVB, is essential for the activation of the sigma factor σ
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Cleavage of an engulfment peptidoglycan hydrolase by a sporulation signature protease in Clostridioides difficile. · full record | OpenQuestion