Evidence map›Paper›PMID 38922498›Full record

ArticleCell biochemistry and biophysics2024

Influence of Cu L-Histidinate Schiff Base Derivatives on Structural Features of Irradiated Rat's DNA.

Nelli H Karapetyan, Samvel G Haroutiunian, Gayane V Ananyan

Abstract read
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In one paragraph

Article in Cell biochemistry and biophysics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nelli H KarapetyanDepartment of Molecular Physics, Yerevan State University, 1 Alex Manoogian St. 0025, Yerevan, Armenia. nelkh@ysu.am.
Samvel G HaroutiunianDepartment of Molecular Physics, Yerevan State University, 1 Alex Manoogian St. 0025, Yerevan, Armenia.
Gayane V AnanyanDepartment of Molecular Physics, Yerevan State University, 1 Alex Manoogian St. 0025, Yerevan, Armenia.

Funding

Higher Education and Science Committee of MESCS RA 21T-1F244
6 · The paper itself

Abstract

A study of rats liver DNA damages under the influence of X-ray radiation at a dose of 6.5 Gy(LD60) was carried out. The radioprotective properties of newly synthesized Cu(II) L-Schiff Histidinate complexes were also studied. The survival of rats was determined over a 30-day period after exposure to X-rays without pretreatment and also after preadministration of Cu(II) L-Histidinate-Schiff base complexes. The structural defects of rat's liver DNA were detected at 3, 7, 14, and 30 days post-irradiation extracted. The results obtained revealed that irradiation with a 6.5Gy dose in the control group degraded the characteristics of rat liver DNA in comparison to healthy DNA. On all investigated experimental days, a decrease in the melting temperature (T

Indexed as

CopperDNADNA DamageHistidineSchiff BasesAnimalsCoordination ComplexesLiverMaleRadiation-Protective AgentsRatsRats, WistarX-RaysCoordination ComplexesCopperDNAHistidineRadiation-Protective AgentsSchiff BasesDNA meltingElectrophoresisIrradiationSchiff base complexes

Identifiers

PMID38922498

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.