Evidence map›Paper›PMID 38922434›Full record

ArticleAnalytical and bioanalytical chemistry2024

Real-world evaluation of a QCM-based biosensor for exhaled air.

Augusto Juste-Dolz, William Teixeira, Yeray Pallás-Tamarit, Mario Carballido-Fernández, Javier Carrascosa, Ángela Morán-Porcar, María Ángeles Redón-Badenas, María Gracia Pla-Roses, María Dolores Tirado-Balaguer, María José Remolar-Quintana and 4 more

Abstract read
In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Augusto Juste-Dolz *Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de València, Universitat de València, Camino de Vera s/n, 46022, Valencia, Spain.
William TeixeiraInstituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de València, Universitat de València, Camino de Vera s/n, 46022, Valencia, Spain.
Yeray Pallás-Tamarit *Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de València, Universitat de València, Camino de Vera s/n, 46022, Valencia, Spain.
Mario Carballido-FernándezHospital General Universitario de Castellón, Avinguda de Benicàssim, 128, 12004, Castellón de la Plana, Spain.
Javier CarrascosaInstituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de València, Universitat de València, Camino de Vera s/n, 46022, Valencia, Spain.
Ángela Morán-PorcarHospital General Universitario de Castellón, Avinguda de Benicàssim, 128, 12004, Castellón de la Plana, Spain.
María Ángeles Redón-BadenasHospital General Universitario de Castellón, Avinguda de Benicàssim, 128, 12004, Castellón de la Plana, Spain.
María Gracia Pla-RosesHospital General Universitario de Castellón, Avinguda de Benicàssim, 128, 12004, Castellón de la Plana, Spain.
María Dolores Tirado-BalaguerHospital General Universitario de Castellón, Avinguda de Benicàssim, 128, 12004, Castellón de la Plana, Spain.
María José Remolar-QuintanaHospital General Universitario de Castellón, Avinguda de Benicàssim, 128, 12004, Castellón de la Plana, Spain.
Jon Ortiz-CarreraLa Fe University and Polytechnic Hospital, Avinguda de Fernando Abril Martorell, nº 106, 46026, Valencia, Spain.
Ethel Ibañez-EchevarríaLa Fe University and Polytechnic Hospital, Avinguda de Fernando Abril Martorell, nº 106, 46026, Valencia, Spain.
Angel MaquieiraInstituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de València, Universitat de València, Camino de Vera s/n, 46022, Valencia, Spain. amaquieira@qim.upv.es.
David Giménez-RomeroDepartamento de Química-Física, Universitat de València, Calle Doctor Moliner 50, 46100, Burjassot, Spain. giroda@uv.es.

Funding

Generalitat Valenciana 2020Generalitat Valenciana DOGV no. 8815Generalitat Valenciana May 19Generalitat Valenciana pp. 16712-16726University of Valencia and INCLIVA|VLC Biomedical Research Institute PI-2021-004
6 · The paper itself

Abstract

The biosensor, named "virusmeter" in this study, integrates quartz crystal microbalance technology with an immune-functionalized chip to distinguish between symptomatic patients with respiratory diseases and healthy individuals by analyzing exhaled air samples. Renowned for its compact design, rapidity, and noninvasive nature, this device yields results within a 5-min timeframe. Evaluated under controlled conditions with 54 hospitalized symptomatic COVID-19 patients and 128 control subjects, the biosensor demonstrated good overall sensitivity (98.15%, 95% CI 90.1-100.0) and specificity (96.87%, 95% CI 92.2-99.1). This proof-of-concept presents an innovative approach with significant potential for leveraging piezoelectric sensors to diagnose respiratory diseases.

Indexed as

Biosensing TechniquesBreath TestsCOVID-19Quartz Crystal Microbalance TechniquesSARS-CoV-2AdultExhalationFemaleHumansMaleMiddle AgedSensitivity and SpecificityBreathalyzerDiagnosisQCMVirusmeter

Identifiers

PMID38922434
PMCPMC11584482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.