Evidence map›Paper›PMID 38922377›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2024

Prevalence and clinical implications of bloodstream infections in intensive care patients with or without burn injury: a retrospective cohort study.

Felix Bergmann, Anselm Jorda, Julia Sollner, Rebecca Sawodny, Kerstin Kammerer, Valerie List, Marlene Prager, Georg Gelbenegger, Katarina Kumpf, Heimo Lagler and 2 more

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Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Felix BergmannDepartment of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria.
Anselm JordaDepartment of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
Julia SollnerDepartment of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria.
Rebecca SawodnyDepartment of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
Kerstin KammererDepartment of Plastic and Reconstructive Surgery, Hospital Wiener Neustadt, Wiener Neustadt, Austria.
Valerie ListDepartment of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
Marlene PragerDepartment of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
Georg GelbeneggerDepartment of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
Katarina KumpfIT Systems and Communications, Medical University of Vienna, Vienna, Austria.
Heimo LaglerDivision of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Markus ZeitlingerDepartment of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
Christine RadtkeDepartment of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria. Christine.radtke@meduniwien.ac.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSevere burn injuries are often accompanied by infections and associated with high morbidity and mortality. This study aimed to compare the prevalence and clinical impact of bacteremia between patients receiving intensive care with and without burns.

methodsThis single-center retrospective cohort study at the University Hospital Vienna, Austria, analyzed blood cultures from intensive care unit (ICU) patients with and without burns (2012-2022) to assess the prevalence of bacteremia, the associated pathogen distribution and the 60-day all-cause mortality.

resultsIn 1170 ICU patients, 303 with burns and 867 without, the prevalence of bacteremia was similar among patients with at least one blood culture (31/157 [19.7%] versus 44/213 [20.7%], OR [95%CI] = 0.95 [0.57-1.57]). Burn patients exhibited a significantly higher frequency of microbiological sampling (51.5% versus 24.5%, p < 0.001), resulting in a higher overall prevalence of bacteremia (10.2% versus 5.1%, p = 0.002). 16.2% of all identified pathogens were multidrug-resistant (MDR). The 60-day all-cause mortality was higher in patients with MDR pathogens than in patients without bacteremia (41.7% versus 10.6%, p = 0.026).

conclusionBacteremia prevalence was similar in burn and non-burn patients, with high rates of multidrug-resistant Gram-negative pathogens. The 60-day all-cause mortality was significantly higher in patients with MDR pathogens than in patients without bacteremia.

Indexed as

BacteremiaBurnsIntensive Care UnitsAdultAgedAnti-Bacterial AgentsAustriaCritical CareDrug Resistance, Multiple, BacterialFemaleHumansMaleMiddle AgedPrevalenceRetrospective StudiesAnti-Bacterial AgentsAntibioticsBacteremiaCritical careICUSepsisThermal injury

Identifiers

PMID38922377
PMCPMC11349827

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.