ArticleEnvironmental health perspectives2024
Association of Gaseous Ambient Air Pollution and Dementia-Related Neuroimaging Markers in the ARIC Cohort, Comparing Exposure Estimation Methods and Confounding by Study Site.
Article in Environmental health perspectives, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Social determinants of health across the lifecourse and chronic disease risk: available data and seminal findings from the Atherosclerosis Risk in Communities (ARIC) Study.American journal of epidemiology · 2026Review
- Accounting for Exposure Measurement Error in Gridded Air Pollution Estimates in Assessing the Association of PMEnvironmental science & technology · 2026Article
- Association between traffic-related air pollution and brain morphology, assessing the olfactory pathway as a mediator.Brain communications · 2026Article
- Ambient air pollution and incident dementia: exploration of relevant exposure windows.Environmental research · 2025Article
- Metabolome informs about the chemical exposome and links to brain health.Environment international · 2025Review
- A bibliometric and systematic review of the global impact of air pollution on Alzheimer's disease: Insights from cohort studies.Journal of Alzheimer's disease reportsReview
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundEvidence linking gaseous air pollution to late-life brain health is mixed.
objectiveWe explored associations between exposure to gaseous pollutants and brain magnetic resonance imaging (MRI) markers among Atherosclerosis Risk in Communities (ARIC) Study participants, with attention to the influence of exposure estimation method and confounding by site.
methodsWe considered data from 1,665 eligible ARIC participants recruited from four US sites in the period 1987-1989 with valid brain MRI data from Visit 5 (2011-2013). We estimated 10-y (2001-2010) mean carbon monoxide (CO), nitrogen dioxide (
resultsWithin-site exposure distributions varied across exposure estimation methods. Meta-analytic associations were generally not statistically significant regardless of exposure, outcome, or exposure estimation method; point estimates often suggested associations between higher DISCUSSION: Patterns of local variation in estimated air pollution concentrations differ by estimation method. Although we did not find strong evidence supporting impact of gaseous pollutants on brain changes detectable by MRI, point estimates suggested associations between higher exposure to CO,
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