Evidence map›Paper›PMID 38922298›Full record

ArticleThe Journal of cell biology2024

Determining how many cells to average for statistical testing of microscopy experiments.

Adam Zweifach

Abstract read
In one paragraph

Article in The Journal of cell biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Adam ZweifachDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA.ORCID 0000-0002-1084-8684

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

From a statistical standpoint, individual cells are typically not independent experimental replicates. To test for differences in mean, cells from each experimental sample can be averaged and each sample's average treated as an n of 1. Here, I outline how to determine how many cells to average per sample.

Indexed as

MicroscopyAnimalsCell CountHumansStatistics as Topic

Identifiers

PMID38922298
PMCPMC11199906

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.