Evidence map›Paper›PMID 38922163›Full record

ArticleToxins2024

Nanostructured Magnetic Particles for Removing Cyanotoxins: Assessing Effectiveness and Toxicity In Vitro.

Alejandro Cao, Natalia Vilariño, Lisandra de Castro-Alves, Yolanda Piñeiro, José Rivas, Ana M Botana, Cristina Carrera, María J Sainz, Luis M Botana

Abstract read
In one paragraph

Article in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alejandro CaoDepartamento de Farmacología, Farmacia y Tecnología Farmacéutica, Facultad de Veterinaria, Universidad de Santiago de Compostela, 27002 Lugo, Spain.ORCID 0000-0002-6134-1373
Natalia VilariñoDepartamento de Farmacología, Farmacia y Tecnología Farmacéutica, Facultad de Veterinaria, Universidad de Santiago de Compostela, 27002 Lugo, Spain.ORCID 0000-0001-6055-6359
Lisandra de Castro-AlvesDepartamento de Física Aplicada, Facultad de Física, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0002-6332-4075
Yolanda PiñeiroDepartamento de Física Aplicada, Facultad de Física, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
José RivasDepartamento de Física Aplicada, Facultad de Física, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0002-5059-3196
Ana M BotanaDepartamento de Química Analítica, Nutrición y Bromatología, Facultad de Ciencias, Universidad de Santiago de Compostela, 27002 Lugo, Spain.
Cristina CarreraDepartamento de Farmacología, Farmacia y Tecnología Farmacéutica, Facultad de Veterinaria, Universidad de Santiago de Compostela, 27002 Lugo, Spain.
María J SainzDepartamento de Producción Vegetal y Proyectos de Ingeniería, Facultad de Veterinaria, Universidad de Santiago de Compostela, 27002 Lugo, Spain.
Luis M BotanaDepartamento de Farmacología, Farmacia y Tecnología Farmacéutica, Facultad de Veterinaria, Universidad de Santiago de Compostela, 27002 Lugo, Spain.ORCID 0000-0003-2153-6608

Funding

Ministerio de Ciencia, Innovación y Universidades PID2020-112626RB-C21
6 · The paper itself

Abstract

The rise in cyanobacterial blooms due to eutrophication and climate change has increased cyanotoxin presence in water. Most current water treatment plants do not effectively remove these toxins, posing a potential risk to public health. This study introduces a water treatment approach using nanostructured beads containing magnetic nanoparticles (MNPs) for easy removal from liquid suspension, coated with different adsorbent materials to eliminate cyanotoxins. Thirteen particle types were produced using activated carbon, CMK-3 mesoporous carbon, graphene, chitosan, 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO)-oxidised cellulose nanofibers (TOCNF), esterified pectin, and calcined lignin as an adsorbent component. The particles' effectiveness for detoxification of microcystin-LR (MC-LR), cylindrospermopsin (CYN), and anatoxin-A (ATX-A) was assessed in an aqueous solution. Two particle compositions presented the best adsorption characteristics for the most common cyanotoxins. In the conditions tested, mesoporous carbon nanostructured particles, P1-CMK3, provide good removal of MC-LR and Merck-activated carbon nanostructured particles, P9-MAC, can remove ATX-A and CYN with high and fair efficacy, respectively. Additionally, in vitro toxicity of water treated with each particle type was evaluated in cultured cell lines, revealing no alteration of viability in human renal, neuronal, hepatic, and intestinal cells. Although further research is needed to fully characterise this new water treatment approach, it appears to be a safe, practical, and effective method for eliminating cyanotoxins from water.

Indexed as

Bacterial ToxinsCyanobacteria ToxinsMarine ToxinsMicrocystinsWater PurificationAdsorptionAlkaloidsCell SurvivalCyanobacteriaHumansMagnetite NanoparticlesNanostructuresTropanesUracilWater Pollutants, ChemicalAlkaloidsanatoxin aBacterial ToxinsCyanobacteria Toxinscyanoginosin LRcylindrospermopsinMagnetite NanoparticlesMarine ToxinsMicrocystinsTropanesUracilWater Pollutants, Chemicalcyanotoxins removaldrinking water safetymagnetic nanoparticles

Identifiers

PMID38922163
PMCPMC11209371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.