Evidence map›Paper›PMID 38921988›Full record

ArticleVeterinary sciences2024

Transcutaneous Auricular Vagal Nerve Stimulation in Healthy Non-Sedated Horses: A Feasibility Study.

Valentina Vitale, Francesca Bindi, Ana Velloso Alvarez, María de la Cuesta-Torrado, Giulia Sala, Micaela Sgorbini

Abstract read
In one paragraph

Article in Veterinary sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Valentina VitaleDepartment of Animal Medicine and Surgery, Institute of Biomedical Sciences, Cardenal Herrera-CEU University, CEU Universities, 46115 Alfara del Patriarca, Spain.ORCID 0000-0003-2273-5377
Francesca BindiDepartment of Veterinary Sciences, University of Pisa, Viale delle Piagge 2, 56122 Pisa, Italy.ORCID 0009-0004-5174-7339
Ana Velloso AlvarezDepartment of Animal Medicine and Surgery, Institute of Biomedical Sciences, Cardenal Herrera-CEU University, CEU Universities, 46115 Alfara del Patriarca, Spain.ORCID 0000-0001-6526-8436
María de la Cuesta-TorradoDepartment of Animal Medicine and Surgery, Institute of Biomedical Sciences, Cardenal Herrera-CEU University, CEU Universities, 46115 Alfara del Patriarca, Spain.ORCID 0009-0001-4183-4226
Giulia SalaDepartment of Veterinary Sciences, University of Pisa, Viale delle Piagge 2, 56122 Pisa, Italy.ORCID 0000-0002-8847-5531
Micaela SgorbiniDepartment of Veterinary Sciences, University of Pisa, Viale delle Piagge 2, 56122 Pisa, Italy.ORCID 0000-0002-0294-1803

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the feasibility of transcutaneous auricular vagal nerve stimulation (tAVNS) in healthy horses and its effect on heart rate variability (HRV). The study comprised three phases: the selection of mares, their acclimatization to the tAVNS, and the stimulation phase. Stimulation was performed with two electrodes positioned on the right pinna. The settings were 0.5 mA, 250 μs, and 25 Hz for pulse amplitude, pulse width, and pulse frequency, respectively. HRV was analysed before (B1), during (T), and after (B2) the tAVNS. From the 44 mares initially included, only 7 completed the three phases. In these mares, the heart rate (HR) was significantly lower, and frequency domain parameters showed an increased parasympathetic tone in B2 compared with B1. However, in 3/7 mares, the HR was significantly higher during T compared with B1 and B2, compatible with a decreased parasympathetic tone, while in 4/7 mares, the HR was significantly lower and the parasympathetic nervous system index was significantly higher during T and B2 compared with B1. The tAVNS is an economical and easy procedure to perform and has the potential to stimulate vagal activity; however, it was poorly tolerated in the mares included in this study.

Indexed as

auricular vagal branchequineparasympathetic activitypost-operative ileustranscutaneous electrical nerve stimulation

Identifiers

PMID38921988
PMCPMC11209208

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.