Evidence map›Paper›PMID 38921945›Full record

ArticleTomography (Ann Arbor, Mich.)2024

Causal Forest Machine Learning Analysis of Parkinson's Disease in Resting-State Functional Magnetic Resonance Imaging.

Gabriel Solana-Lavalle, Michael D Cusimano, Thomas Steeves, Roberto Rosas-Romero, Pascal N Tyrrell

Abstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. AI in Medical Imaging and Image Processing.Journal of clinical medicine · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabriel Solana-LavalleDepartment of Computing, Electronics, and Mechatronics, Universidad de las Américas Puebla Santa Catarina Mártir, San Andrés Cholula, Puebla 78210, Mexico.ORCID 0000-0002-3026-8732
Michael D CusimanoInstitute of Medical Science, University of Toronto, Toronto, ON M5S 1A1, Canada.
Thomas SteevesDivision of Neurology, Unity Health Toronto, St. Michael's Hospital, Toronto, ON M5B 1W8, Canada.
Roberto Rosas-RomeroDepartment of Computing, Electronics, and Mechatronics, Universidad de las Américas Puebla Santa Catarina Mártir, San Andrés Cholula, Puebla 78210, Mexico.ORCID 0000-0001-6118-3347
Pascal N TyrrellDepartment of Medical Imaging, University of Toronto, Toronto, ON M5S 1A1, Canada.ORCID 0000-0003-2277-3824

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, Artificial Intelligence has been used to assist healthcare professionals in detecting and diagnosing neurodegenerative diseases. In this study, we propose a methodology to analyze functional Magnetic Resonance Imaging signals and perform classification between Parkinson's disease patients and healthy participants using Machine Learning algorithms. In addition, the proposed approach provides insights into the brain regions affected by the disease. The functional Magnetic Resonance Imaging from the PPMI and 1000-FCP datasets were pre-processed to extract time series from 200 brain regions per participant, resulting in 11,600 features. Causal Forest and Wrapper Feature Subset Selection algorithms were used for dimensionality reduction, resulting in a subset of features based on their heterogeneity and association with the disease. We utilized Logistic Regression and XGBoost algorithms to perform PD detection, achieving 97.6% accuracy, 97.5% F

Indexed as

Machine LearningMagnetic Resonance ImagingParkinson DiseaseAgedAlgorithmsBrainFemaleHumansMaleMiddle AgedCausal Forestcomputer-assistedfunctional Magnetic Resonance ImagingMachine LearningMultiple Correspondence AnalysisParkinson’s disease detection

Identifiers

PMID38921945
PMCPMC11209036

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.