Evidence map›Paper›PMID 38921824›Full record

ArticleeLife2024

RNA polymerase III is involved in regulating

Gretchen Diffendall, Aurelie Claes, Anna Barcons-Simon, Prince Nyarko, Florent Dingli, Miguel M Santos, Damarys Loew, Antoine Claessens, Artur Scherf

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gretchen DiffendallInstitut Pasteur, Universite Paris Cité, Paris, France.ORCID https://orcid.org/0000-0002-0783-517X
Aurelie ClaesInstitut Pasteur, Universite Paris Cité, Paris, France.
Anna Barcons-SimonInstitut Pasteur, Universite Paris Cité, Paris, France.
Prince NyarkoInstitut Pasteur, Laboratory of Pathogen-Host Interaction (LPHI), CNRS, University of Montpellier, Montpellier, France.
Florent DingliInstitut Pasteur, Institut Curie, PSL Research University, Centre de Recherche, CurieCoreTech Mass Spectrometry Proteomics, Paris, France.
Miguel M SantosInstitut Pasteur, Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal.ORCID https://orcid.org/0000-0002-5594-2682
Damarys LoewInstitut Pasteur, Institut Curie, PSL Research University, Centre de Recherche, CurieCoreTech Mass Spectrometry Proteomics, Paris, France.ORCID https://orcid.org/0000-0002-9111-8842
Antoine ClaessensInstitut Pasteur, Laboratory of Pathogen-Host Interaction (LPHI), CNRS, University of Montpellier, Montpellier, France.ORCID https://orcid.org/0000-0002-4277-0914
Artur ScherfInstitut Pasteur, Universite Paris Cité, Paris, France.ORCID https://orcid.org/0000-0003-2411-3328

Funding

Agence Nationale de la Recherche 18-CE15-0009-01Agence Nationale de la Recherche ANR-11-LABX-0024European Research Council AdG PlasmoSilencing 670301
6 · The paper itself

Abstract

While often undetected and untreated, persistent seasonal asymptomatic malaria infections remain a global public health problem. Despite the presence of parasites in the peripheral blood, no symptoms develop. Disease severity is correlated with the levels of infected red blood cells (iRBCs) adhering within blood vessels. Changes in iRBC adhesion capacity have been linked to seasonal asymptomatic malaria infections, however how this is occurring is still unknown. Here, we present evidence that RNA polymerase III (RNA Pol III) transcription in

Indexed as

Malaria, FalciparumPlasmodium falciparumRNA Polymerase IIICell AdhesionErythrocytesGene Expression RegulationHumansProtozoan ProteinsVirulenceVirulence FactorsProtozoan ProteinsRNA Polymerase IIIVirulence Factorsinfectious diseasemalariamicrobiologyncRNAP. falciparumvar genesvirulence

Identifiers

PMID38921824
PMCPMC11208047

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.