Evidence map›Paper›PMID 38921797›Full record

ArticlePathogens (Basel, Switzerland)2024

Cytomegalovirus, Epstein-Barr Virus, Herpes Simplex Virus, and Varicella Zoster Virus Infection Dynamics in People with Multiple Sclerosis from Northern Italy.

Peter A Maple, Radu Tanasescu, Cris S Constantinescu, Paola Valentino, Marco Capobianco, Silvia D'Orso, Giovanna Borsellino, Luca Battistini, Giovanni Ristori, Rosella Mechelli and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Peter A MapleMental Health and Clinical Neuroscience Academic Unit, University of Nottingham School of Medicine, Nottingham NG7 2UH, UK.ORCID 0000-0002-5534-5191
Radu TanasescuMental Health and Clinical Neuroscience Academic Unit, University of Nottingham School of Medicine, Nottingham NG7 2UH, UK.ORCID 0000-0003-2282-1793
Cris S ConstantinescuMental Health and Clinical Neuroscience Academic Unit, University of Nottingham School of Medicine, Nottingham NG7 2UH, UK.ORCID 0000-0003-2066-7585
Paola ValentinoNeuroscience Institute, Cavalieri Ottolenghi, 10043 Orbassano, Italy.ORCID 0000-0003-3819-9409
Marco CapobiancoNeuroscience Institute, Cavalieri Ottolenghi, 10043 Orbassano, Italy.
Silvia D'OrsoDepartment of Experimental Neuroscience, IRCSS Foundation Santa Lucia, 00179 Rome, Italy.
Giovanna BorsellinoDepartment of Experimental Neuroscience, IRCSS Foundation Santa Lucia, 00179 Rome, Italy.ORCID 0000-0002-4227-6481
Luca BattistiniDepartment of Experimental Neuroscience, IRCSS Foundation Santa Lucia, 00179 Rome, Italy.ORCID 0000-0002-6488-4891
Giovanni RistoriDepartment of Experimental Neuroscience, IRCSS Foundation Santa Lucia, 00179 Rome, Italy.
Rosella MechelliDepartment of Human Science and Promotion of Quality of Life, San Raffaele Open University, 00166 Rome, Italy.ORCID 0000-0001-5842-3100
Marco SalvettiDepartment of Neurosciences, Mental Health and Sensory Organs, Centre for Experimental Neurological Therapies (CENTERS), Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-0501-8803
Bruno GranMental Health and Clinical Neuroscience Academic Unit, University of Nottingham School of Medicine, Nottingham NG7 2UH, UK.ORCID 0000-0001-6384-2342

Funding

Italian Multiple SclerosisFoundation 2020 R-Multi 050Medical Research Council MR/T024402/1
6 · The paper itself

Abstract

Previous exposure to Epstein-Barr virus (EBV) is strongly associated with the development of multiple sclerosis (MS). By contrast, past cytomegalovirus (CMV) infection may have no association, or be negatively associated with MS. This study aimed to investigate the associations of herpesvirus infections with MS in an Italian population. Serum samples (

Indexed as

Antibodies, ViralCytomegalovirusEpstein-Barr Virus InfectionsHerpesvirus 3, HumanHerpesvirus 4, HumanImmunoglobulin GMultiple SclerosisAdultCytomegalovirus InfectionsFemaleHerpes SimplexHumansItalyMaleMiddle AgedSeroepidemiologic StudiesAntibodies, ViralImmunoglobulin Gantibody levelscytomegalovirusEpstein–Barr virusherpes simplex virushuman herpesvirusesItalymultiple sclerosisseroprevalencevaricella zoster virus

Identifiers

PMID38921797
PMCPMC11206421

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.