Evidence map›Paper›PMID 38921768›Full record

SynthesisPathogens (Basel, Switzerland)2024

Human Placental Schistosomiasis-A Systematic Review of the Literature.

Jacob Gerstenberg, Sasmita Mishra, Martha Holtfreter, Joachim Richter, Saskia Dede Davi, Dearie Glory Okwu, Michael Ramharter, Johannes Mischlinger, Benjamin T Schleenvoigt, TropNet

Abstract readSystematic Review
In one paragraph

Synthesis in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Physiological stage-dependent effects ofFrontiers in microbiology · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jacob GerstenbergInstitute for Tropical Medicine, Eberhard-Karls University Tübingen, 72074 Tübingen, Germany.ORCID 0009-0008-1604-9710
Sasmita MishraDepartment of Obstetrics and Gynecology, Heidekreis Klinikum, 29664 Walsrode, Germany.
Martha HoltfreterTropical Medicine Unit, Department of Gastroenterology, Hepatology and Infectious Diseases, Faculty of Medicine, Heinrich-Heine-University, Moorenstr. 5, 40225 Duesseldorf, Germany.
Joachim RichterInstitute of International Health, Global Health Center, Charité University Medicine, 13353 Berlin, Germany.ORCID 0000-0002-1930-2944
Saskia Dede DaviCenter for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, 20359 Hamburg, Germany.
Dearie Glory OkwuCentre de Recherches Médicales de Lambaréné, Lambaréné 242, Gabon.ORCID 0000-0002-4025-2320
Michael RamharterCenter for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, 20359 Hamburg, Germany.
Johannes MischlingerCenter for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, 20359 Hamburg, Germany.ORCID 0000-0002-2012-6327
Benjamin T SchleenvoigtInstitute of Infectious Diseases and Infection Control, Jena University Hospital, Friedrich-Schiller-University, 07747 Jena, Germany.ORCID 0000-0003-4678-2469
TropNet

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSchistosome egg deposition in pregnant women may affect the placenta of infected mothers and cause placental schistosomiasis (PS). Histopathological examination of placental tissue is an inadequate detection method due to low sensitivity. So far, there has not been any systematic review on PS.

methodsWe conducted a systematic literature search on PubMed, EMBASE, and Medline and included all publications that reported microscopically confirmed cases of PS, as well as the relevant secondary literature found in the citations of the primarily included publications.

resultsOut of 113 abstracts screened we found a total of 8 publications describing PS with a total of 92 cases describing egg deposition of dead and/or viable eggs and worms of

conclusionsPS is a highly unattended and underdiagnosed condition in endemic populations, due to a lack of awareness as well as low sensitivity of histopathological examinations. However, PS may play an important role in mediating or reinforcing adverse birth outcomes (ABO) such as fetal growth restriction (FGR) in maternal schistosomiasis, possibly by placental inflammation.

Indexed as

PlacentaPregnancy Complications, ParasiticAnimalsCross-Sectional StudiesFemaleHumansPlacenta DiseasesPregnancyPrevalenceSchistosoma haematobiumSchistosoma mansoniSchistosomiasisadverse birth outcomesplacentapraziquantelpregnancyschistosomiasis

Identifiers

PMID38921768
PMCPMC11206619

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.