Evidence map›Paper›PMID 38921569›Full record

ArticleMarine drugs2024

Distribution and Level of Bioactive Monoacylglycerols in 12 Marine Microalgal Species.

Giovanna Santaniello, Gianna Falascina, Marcello Ziaco, Laura Fioretto, Angela Sardo, Martina Carelli, Mariarosaria Conte, Giovanna Romano, Adele Cutignano

Abstract read
In one paragraph

Article in Marine drugs, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giovanna SantanielloStazione Zoologica Anton Dohrn, Ecosustainable Marine Biotechnology Department, via Acton 55, 80133 Naples, Italy.
Gianna FalascinaNational Research Council (CNR), Institute of Biomolecular Chemistry (ICB), via Campi Flegrei 34, 80078 Pozzuoli, Italy.
Marcello ZiacoNational Research Council (CNR), Institute of Biomolecular Chemistry (ICB), via Campi Flegrei 34, 80078 Pozzuoli, Italy.ORCID 0000-0002-0054-779X
Laura FiorettoNational Research Council (CNR), Institute of Biomolecular Chemistry (ICB), via Campi Flegrei 34, 80078 Pozzuoli, Italy.ORCID 0000-0003-3876-6100
Angela SardoStazione Zoologica Anton Dohrn, Ecosustainable Marine Biotechnology Department, via Acton 55, 80133 Naples, Italy.ORCID 0000-0002-9355-0487
Martina CarelliNational Research Council (CNR), Institute of Biomolecular Chemistry (ICB), via Campi Flegrei 34, 80078 Pozzuoli, Italy.
Mariarosaria ConteDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Vico L. De Crecchio 7, 80138 Naples, Italy.ORCID 0000-0002-3622-1476
Giovanna RomanoStazione Zoologica Anton Dohrn, Ecosustainable Marine Biotechnology Department, via Acton 55, 80133 Naples, Italy.ORCID 0000-0002-4898-7153
Adele CutignanoStazione Zoologica Anton Dohrn, Ecosustainable Marine Biotechnology Department, via Acton 55, 80133 Naples, Italy.ORCID 0000-0003-3035-9252

Funding

National Biodiversity Future Centre (NBFC) Program, Italian Ministry of University and Research, PNRR, Missione 4 Componente 2 Investimento 1.4 CN00000033
6 · The paper itself

Abstract

Microalgae are currently considered an attractive source of highly valuable metabolites potentially exploitable as anticancer agents, nutraceuticals and cosmeceuticals and for bioenergy purposes. Their ease of culturing and their high growth rates further promote their use as raw material for the production of specialty products. In the present paper, we focused our attention on specific glycerol-based lipid compounds, monoacylglycerols (MAGs), which displayed in our previous studies a selective cytotoxic activity against the haematological U-937 and the colon HCT-116 cancer cell lines. Here, we performed a quali/quantitative analysis of MAGs and total fatty acids (FAs) along with a profiling of the main lipid classes in a panel of 12 microalgal species, including diatoms and dinoflagellates. Our results highlight an inter- and intraspecific variability of MAG profile in the selected strains. Among them,

Indexed as

Fatty AcidsMicroalgaeMonoglyceridesAntineoplastic AgentsAquatic OrganismsCell Line, TumorDiatomsDinoflagellidaHCT116 CellsHumansAntineoplastic AgentsFatty AcidsMonoglyceridesfatty acid analysisGC-MSmicroalgaequantitative MAG analysisUHPLC-Q-Exactiveuntargeted lipid analysis

Identifiers

PMID38921569
PMCPMC11205161

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.