Evidence map›Paper›PMID 38921546›Full record

ArticleMarine drugs2024

Methanolic Extract and Brominated Compound from the Brazilian Marine Sponge

Catarina de Jesus Nunes, Cinthia Cristina Santos, Erica Novaes Soares, Irlã Santos Lima, Uesley Vieira Alves, Emílio Lanna, Ronan Batista, Ravena Pereira do Nascimento, Silvia Lima Costa

Abstract read
In one paragraph

Article in Marine drugs, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Catarina de Jesus NunesLaboratory of Neurochemistry and Cell Biology (LabNq), Department of Biochemistry and Biophysics, Institute of Science and Health, Federal University of Bahia, Salvador 40231-300, Bahia, Brazil.
Cinthia Cristina SantosLaboratory of Neurochemistry and Cell Biology (LabNq), Department of Biochemistry and Biophysics, Institute of Science and Health, Federal University of Bahia, Salvador 40231-300, Bahia, Brazil.
Erica Novaes SoaresLaboratory of Neurochemistry and Cell Biology (LabNq), Department of Biochemistry and Biophysics, Institute of Science and Health, Federal University of Bahia, Salvador 40231-300, Bahia, Brazil.
Irlã Santos LimaLaboratory of Neurochemistry and Cell Biology (LabNq), Department of Biochemistry and Biophysics, Institute of Science and Health, Federal University of Bahia, Salvador 40231-300, Bahia, Brazil.
Uesley Vieira AlvesLaboratory of Research in Bioactive Substances (LAPESBI), Department of Organic Chemistry, Institute of Chemistry, Federal University of Bahia, Salvador 40170-115, Bahia, Brazil.
Emílio LannaBiology Institute, Federal University of Bahia, Salvador 40170-115, Bahia, Brazil.
Ronan BatistaLaboratory of Research in Bioactive Substances (LAPESBI), Department of Organic Chemistry, Institute of Chemistry, Federal University of Bahia, Salvador 40170-115, Bahia, Brazil.ORCID 0000-0003-3401-6054
Ravena Pereira do NascimentoLaboratory of Neurochemistry and Cell Biology (LabNq), Department of Biochemistry and Biophysics, Institute of Science and Health, Federal University of Bahia, Salvador 40231-300, Bahia, Brazil.ORCID 0000-0002-2915-3030
Silvia Lima CostaLaboratory of Neurochemistry and Cell Biology (LabNq), Department of Biochemistry and Biophysics, Institute of Science and Health, Federal University of Bahia, Salvador 40231-300, Bahia, Brazil.ORCID 0000-0002-8975-3871

Funding

National Council for Scientific and Technological Development 131673/2021-1National Council for Scientific and Technological Development 312388/2021-7National Council for Scientific and Technological Development National Institute for Translational Neuroscience Brazil
6 · The paper itself

Abstract

Neurodegenerative diseases involve neuroinflammation and a loss of neurons, leading to disability and death. Hence, the research into new therapies has been focused on the modulation of the inflammatory response mainly by microglia/macrophages. The extracts and metabolites of marine sponges have been presented as anti-inflammatory. This study evaluated the toxicity of an extract and purified compound from the Brazilian marine sponge

Indexed as

MicrogliaNeuroprotective AgentsPoriferaAnimalsAnti-Inflammatory AgentsBrazilHydrocarbons, BrominatedInflammationPC12 CellsRatsAnti-Inflammatory AgentsHydrocarbons, BrominatedNeuroprotective Agents3,5-dibromoverongiaquinol dimethyl ketalanti-neuroinflammatoryAplysina fulvamarine spongesneuroprotection

Identifiers

PMID38921546
PMCPMC11204514

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.