ArticleJournal of functional biomaterials2024
Osteoinductive Properties of Autologous Dentin: An Ex Vivo Study on Extracted Teeth.
Article in Journal of functional biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Geometry-Dependent Osteogenic Performance of Demineralized Dentin Matrix as a Carrier for rhBMP-2.Tissue engineering and regenerative medicine · 2026Article
- Controlled Impact Fragmentation of Extracted Teeth as a Novel Strategy for Dentin Graft Preparation: A Granulometric and Comparative Study.Materials (Basel, Switzerland) · 2026Article
- Comparative Analysis of the Osteogenic Potential of Long-Term Dry-Stored Deciduous and Fresh Permanent Tooth-Derived Dentin Matrix.Materials (Basel, Switzerland) · 2026Article
- Split-Mouth Comparison Between Autologous Dentin and Heterologous Bone in Bone Regeneration: Clinical Study on 15 Patients.Clinical and experimental dental research · 2026Article
- Direct Pulp Capping of Dental Pulp with Two Different Autologous Platelet Concentrates A-PRF+ and H-PRF-A Report on Two Cases.Dentistry journal · 2026Article
- Optimizing Alveolar Ridge Preservation and GBR: A Systematic Review of Membranes, Grafts, and Soft Tissue Strategies for Personalized Care.International journal of dentistry · 2026Review
- Functional Biomaterials for Regenerative Dentistry.Journal of functional biomaterials · 2025Article
- Article
- Histological Analysis of Sticky Tooth and Sticky Bone.Journal of functional biomaterials · 2025Article
- Comparative Histological Analysis of Dentine-Derived Tooth Grafts in Maxillary vs Mandibular Socket Preservation: A Retrospective Study of 178 Cases.Dentistry journal · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the last decades, a variety of biomaterials, ranging from synthetic products to autologous and heterologous grafts, have been recommended to conserve and regenerate bone tissue after tooth extraction. We conducted a biochemical study on ground extracted teeth that aimed to evaluate the osteoinductive and osteoconductive potential of dentin by assessing the releases of bone morphogenetic protein (BMP-2), osteocalcin (OC) and osteonectin (ON) over time (24 h, 10 days and 28 days). Twenty-six patients, who required the extraction of nonrestorable teeth, were enrolled in the study according to the inclusion criteria, as follows: thirteen young patients 18 to 49 years of age (UNDER 50), and thirteen patients of 50 to 70 years (OVER 50); a total of twenty-six teeth were extracted, ground and analyzed by enzyme-linked immunosorbent assays (ELISA). All ground teeth released BMP-2, OC and ON at each time point; no differences were observed between the UNDER-50 and OVER-50 patients. The results of the study support the use of autologous dentin as osteoinductive material for bone regeneration procedures, irrespective of patients' ages.
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