ArticleJournal of functional biomaterials2024
Effect of Calcium Silicate-Based Intracanal Medicament and Calcium Hydroxide on Growth Factor TGF-β1 Release from Root Canal Dentine.
Article in Journal of functional biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Effect of Er, Cr: YSGG laser-activated final irrigation on gingival crevicular fluid RANKL/OPG levels.Scientific reports · 2025Trial
- Efficacy of Calcium Silicate-Based, Simvastatin, Levofloxacin and Calcium Hydroxide Intracanal Medicaments Against Mature Enterococcus faecalis Biofilm. An In Vitro Study.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026Article
- Wnt/β-Catenin Pathway and Hydraulic Calcium Silicate-Based Cements: A Narrative Review.Dentistry journal · 2026Review
- Assessment of the dentine microhardness following the application of different intracanal medicaments. An in-vitro study.BDJ open · 2026Article
- Bioactive Materials and Novel Techniques in Endodontics: Translational Advances for Clinical Practice.Journal of functional biomaterials · 2026Article
- Next-Gen Restorative Materials to Revolutionise Smiles.Bioengineering (Basel, Switzerland) · 2026Review
- Regenerative Endodontic Procedure (REP) of a Previously Treated, Infected, Immature Permanent Incisor.Case reports in dentistry · 2026Article
- Effect of Chitosan and bioactive glass nanomaterials as intracanal medicaments on TGF-β1 release from intraradicular dentin.BMC oral health · 2025Article
- Comparative evaluation of transforming growth factor-beta 1 release from dentin matrix with double antibiotic paste, probiotics, and simvastatin as intracanal medicaments: AnJournal of conservative dentistry and endodontics · 2025Article
- Injectable thermosensitive antibiotic-laden chitosan hydrogel for regenerative endodontics.Bioactive materials · 2025Article
- Benzyl isothiocyanate exhibits antibacterial and antibiofilm activity againstFrontiers in cellular and infection microbiology · 2025Article
- Antibiofilm efficacy of a calcium silicate-based intracanal medicament against Fusobacterium nucleatum strains.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Effective root canal disinfection and the subsequent release of natural growth factors from dentin are crucial to the success of regenerative endodontic procedures. This study evaluated the effect of newly introduced calcium silicate-based temporary intracanal medicament Bio-C Temp and calcium hydroxide-based material UltraCal XS on the release of transforming growth factor β1 (TGF-β1) from root canal dentin. Twenty-two intact and fully developed human premolars from patients aged 15-18 were shaped and irrigated according to the current clinical recommendations. The teeth were then gently split in half, and the root canal dentin of paired samples was covered with Bio-C Temp or UltraCal XS. After 3 weeks of incubation, the specimens were conditioned with 17% EDTA and the collected solution was subjected to the quantification of the released TGF-β1 by performing an ELISA. One-way analysis of variance (ANOVA), followed by Tukey's test, was selected to determine the statistically significant differences between the groups at the 0.95 confidence level. The highest mean value of released TGF-β1 (1993.1 pg/mL) was detected in the control group, where the root canal dentin was conditioned with 17% EDTA alone. Regarding the experimental groups, Bio-C Temp released a statistically significantly higher amount of TGF-β1 (282.14 pg/mL) compared to UltraCal XS (114.28 pg/mL;
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Registered trials
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